| SP | Arrieta, J.Arrieta, Jake >> | 30 | 2016 | R | 94 | 30 | 30 | 7 | 10 | 4.04 | .313 | 1.34 | 8.1 | 4.0 | 7.5 | 198.1 | 178 | 93 | 89 | 15 | 87 | 165 | 0 | 0 | 0 | 0 | 20 | 6 | 12 | 3.73 |
| SP | Moore, M.Moore, Matt # >> | 27 | 2016 | L | 59 | 30 | 30 | 13 | 11 | 3.94 | .296 | 1.23 | 8.2 | 2.8 | 8.0 | 194.0 | 177 | 87 | 85 | 17 | 61 | 173 | 1 | 0 | 0 | 0 | 20 | 7 | 4 | 3.41 |
| SP | Tillman, C.Tillman, Chris >> | 28 | 2016 | R | 59 | 29 | 29 | 9 | 10 | 5.50 | .346 | 1.53 | 9.6 | 4.3 | 6.3 | 160.1 | 170 | 104 | 98 | 24 | 76 | 112 | 0 | 0 | 0 | 0 | 11 | 9 | 8 | 5.14 |
| SP | Bauer, T.Bauer, Trevor >> | 25 | 2016 | R | 56 | 29 | 29 | 13 | 8 | 3.74 | .316 | 1.36 | 8.1 | 4.1 | 8.8 | 168.2 | 152 | 76 | 70 | 17 | 77 | 165 | 0 | 0 | 0 | 0 | 14 | 5 | 2 | 3.82 |
| SP | Sabathia, C.Sabathia, CC # >> | 36 | 2016 | L | 51 | 28 | 28 | 4 | 12 | 7.55 | .388 | 1.85 | 12.4 | 4.3 | 7.0 | 152.2 | 210 | 132 | 128 | 28 | 72 | 119 | 0 | 0 | 0 | 0 | 9 | 8 | 4 | 5.41 |
| RP | Familia, J.Familia, Jeurys >> | 26 | 2016 | R | 53 | 75 | 0 | 4 | 1 | 3.59 | .329 | 1.44 | 8.7 | 4.3 | 11.4 | 92.2 | 89 | 37 | 37 | 7 | 44 | 117 | 0 | 8 | 6 | 0 | 0 | 3 | 6 | 2.98 |
| SP | Anderson, C.Anderson, Chase >> | 28 | 2016 | R | 35 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Colon, B.Colon, Bartolo >> | 43 | 2016 | R | 49 | 46 | 0 | 4 | 8 | 7.60 | .360 | 1.64 | 12.7 | 2.0 | 6.2 | 58.0 | 82 | 49 | 49 | 9 | 13 | 40 | 0 | 8 | 3 | 0 | 0 | 3 | 0 | 4.47 |