| SP | Kluber, C.Kluber, Corey >> | 30 | 2016 | R | 95 | 16 | 16 | 4 | 7 | 3.48 | .317 | 1.31 | 8.6 | 3.2 | 8.1 | 103.1 | 98 | 42 | 40 | 9 | 37 | 93 | 0 | 0 | 0 | 0 | 11 | 9 | 3 | 3.67 |
| SP | Manaea, S.Manaea, Sean >> | 24 | 2016 | L | 69 | 16 | 16 | 7 | 7 | 4.20 | .338 | 1.48 | 10.3 | 3.2 | 8.6 | 85.2 | 97 | 40 | 40 | 6 | 30 | 81 | 0 | 0 | 0 | 0 | 6 | 4 | 3 | 3.21 |
| SP | Tillman, C.Tillman, Chris # >> | 28 | 2016 | R | 59 | 15 | 15 | 5 | 2 | 4.24 | .341 | 1.49 | 9.3 | 4.2 | 7.9 | 80.2 | 83 | 39 | 38 | 11 | 37 | 70 | 0 | 0 | 0 | 0 | 8 | 5 | 3 | 4.61 |
| SP | Shoemaker, M.Shoemaker, Matt >> | 29 | 2016 | R | 58 | 15 | 15 | 4 | 6 | 4.43 | .318 | 1.36 | 9.6 | 2.7 | 8.1 | 87.1 | 93 | 46 | 43 | 8 | 26 | 78 | 0 | 0 | 0 | 0 | 8 | 3 | 2 | 3.40 |
| RP | Colome, A.Colome, Alex >> | 27 | 2016 | R | 77 | 42 | 0 | 0 | 2 | 2.45 | .270 | 1.07 | 7.0 | 2.6 | 10.1 | 55.0 | 43 | 17 | 15 | 3 | 16 | 62 | 0 | 5 | 3 | 0 | 0 | 2 | 1 | 2.44 |
| RP | Grilli, J.Grilli, Jason >> | 40 | 2016 | R | 55 | 39 | 0 | 3 | 3 | 3.55 | .338 | 1.53 | 7.0 | 7.0 | 9.8 | 45.2 | 35 | 18 | 18 | 3 | 35 | 49 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 4.02 |
| RP | Johnson, J.Johnson, Jim >> | 33 | 2016 | R | 46 | 36 | 0 | 2 | 2 | 2.85 | .309 | 1.29 | 6.8 | 4.8 | 10.3 | 41.0 | 31 | 17 | 13 | 3 | 22 | 47 | 0 | 4 | 1 | 0 | 0 | 2 | 1 | 3.41 |
| SP | Greinke, Z.Greinke, Zack >> | 33 | 2016 | R | 49 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Sabathia, C.Sabathia, CC >> | 36 | 2016 | L | 51 | 6 | 0 | 0 | 1 | 3.12 | .297 | 1.27 | 11.3 | 1.1 | 7.9 | 8.2 | 10 | 4 | 3 | 1 | 1 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.25 |
| SP | Tomlin, J.Tomlin, Josh >> | 31 | 2016 | R | 52 | 23 | 0 | 1 | 4 | 5.86 | .352 | 1.60 | 12.8 | 1.7 | 7.1 | 43.0 | 61 | 28 | 28 | 7 | 8 | 34 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 4.16 |