| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 100 | 36 | 36 | 16 | 10 | 3.46 | .274 | 1.09 | 8.1 | 1.7 | 9.7 | 257.1 | 232 | 102 | 99 | 31 | 49 | 277 | 4 | 0 | 0 | 2 | 23 | 11 | 6 | 3.11 |
| SP | Cueto, J.Cueto, Johnny # >> | 30 | 2016 | R | 87 | 34 | 34 | 11 | 11 | 4.08 | .309 | 1.31 | 9.5 | 2.3 | 8.0 | 227.0 | 240 | 114 | 103 | 30 | 57 | 201 | 2 | 0 | 0 | 1 | 22 | 8 | 0 | 3.81 |
| SP | Roark, T.Roark, Tanner >> | 29 | 2016 | R | 80 | 33 | 33 | 15 | 8 | 4.22 | .322 | 1.39 | 8.7 | 3.8 | 7.8 | 204.2 | 198 | 107 | 96 | 21 | 86 | 176 | 1 | 0 | 0 | 0 | 18 | 7 | 5 | 3.98 |
| SP | Archer, C.Archer, Chris # >> | 27 | 2016 | R | 71 | 33 | 33 | 10 | 14 | 5.15 | .352 | 1.60 | 10.7 | 3.7 | 10.0 | 183.1 | 217 | 111 | 105 | 27 | 76 | 204 | 0 | 0 | 0 | 0 | 16 | 6 | 7 | 4.03 |
| SP | Santana, E.Santana, Ervin >> | 33 | 2016 | R | 65 | 31 | 31 | 9 | 13 | 6.42 | .371 | 1.73 | 12.1 | 3.5 | 7.5 | 169.2 | 227 | 127 | 121 | 27 | 66 | 140 | 0 | 0 | 0 | 0 | 11 | 7 | 4 | 4.72 |
| RP | Devenski, C.Devenski, Chris † >> | 25 | 2016 | R | 87 | 78 | 0 | 9 | 2 | 3.42 | .285 | 1.18 | 8.2 | 2.5 | 7.8 | 123.2 | 112 | 48 | 47 | 9 | 34 | 107 | 0 | 10 | 3 | 0 | 0 | 2 | 1 | 3.09 |
| RP | Herrera, K.Herrera, Kelvin >> | 26 | 2016 | R | 79 | 43 | 0 | 2 | 1 | 2.65 | .264 | 1.04 | 6.9 | 2.5 | 11.3 | 51.0 | 39 | 15 | 15 | 4 | 14 | 64 | 0 | 0 | 1 | 0 | 0 | 2 | 5 | 2.45 |
| RP | Barraclough, K.Barraclough, Kyle >> | 26 | 2016 | R | 70 | 30 | 0 | 2 | 1 | 2.83 | .338 | 1.50 | 6.8 | 7.1 | 11.3 | 28.2 | 21 | 11 | 9 | 1 | 22 | 35 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 3.43 |
| RP | Belisle, M.Belisle, Matt >> | 36 | 2016 | R | 47 | 16 | 0 | 1 | 1 | 2.57 | .213 | 0.76 | 5.6 | 1.3 | 5.6 | 21.0 | 13 | 6 | 6 | 2 | 3 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.57 |
| RP | Diekman, J.Diekman, Jake >> | 29 | 2016 | L | 69 | 17 | 0 | 1 | 0 | 0.57 | .309 | 1.21 | 7.2 | 4.2 | 15.0 | 15.2 | 12 | 1 | 1 | 1 | 7 | 25 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 2.33 |
| RP | Feliz, M.Feliz, Michael >> | 23 | 2016 | R | 60 | 24 | 0 | 0 | 0 | 6.03 | .347 | 1.53 | 11.3 | 2.6 | 11.6 | 31.1 | 39 | 21 | 21 | 4 | 9 | 40 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 3.16 |
| CL | Thornburg, T.Thornburg, Tyler >> | 27 | 2016 | R | 96 | 66 | 0 | 4 | 15 | 4.79 | .337 | 1.45 | 8.2 | 5.0 | 11.0 | 67.2 | 61 | 37 | 36 | 10 | 37 | 82 | 0 | 32 | 8 | 0 | 0 | 5 | 5 | 4.37 |