| SP | Bumgarner, M.Bumgarner, Madison † >> | 26 | 2016 | L | 97 | 36 | 36 | 13 | 10 | 3.15 | .266 | 1.05 | 7.7 | 1.8 | 9.8 | 234.0 | 199 | 82 | 82 | 31 | 46 | 256 | 0 | 0 | 0 | 0 | 25 | 9 | 2 | 3.24 |
| SP | Fernandez, J.Fernandez, Jose >> | 24 | 2016 | R | 90 | 36 | 36 | 11 | 13 | 4.52 | .317 | 1.32 | 8.7 | 3.2 | 9.5 | 199.1 | 193 | 103 | 100 | 24 | 70 | 210 | 1 | 0 | 0 | 0 | 18 | 14 | 6 | 3.72 |
| SP | Syndergaard, N.Syndergaard, Noah >> | 23 | 2016 | R | 83 | 33 | 33 | 14 | 9 | 3.68 | .296 | 1.21 | 8.5 | 2.4 | 10.1 | 203.0 | 192 | 83 | 83 | 15 | 54 | 228 | 0 | 0 | 0 | 0 | 22 | 10 | 4 | 2.66 |
| SP | Martinez, C.Martinez, Carlos # >> | 25 | 2016 | R | 74 | 34 | 33 | 14 | 9 | 3.64 | .316 | 1.32 | 9.2 | 2.7 | 7.6 | 195.1 | 199 | 84 | 79 | 16 | 58 | 164 | 0 | 0 | 0 | 0 | 20 | 14 | 7 | 3.49 |
| SP | Wright, S.Wright, Steven # >> | 31 | 2016 | R | 66 | 31 | 30 | 9 | 12 | 4.60 | .333 | 1.45 | 9.3 | 3.7 | 6.4 | 186.0 | 193 | 97 | 95 | 31 | 77 | 132 | 1 | 0 | 0 | 0 | 16 | 8 | 5 | 5.12 |
| CL | Miller, A.Miller, Andrew † >> | 31 | 2016 | L | 100 | 83 | 0 | 8 | 5 | 3.41 | .285 | 1.14 | 7.8 | 2.5 | 10.4 | 87.0 | 75 | 34 | 33 | 16 | 24 | 101 | 0 | 45 | 7 | 0 | 0 | 5 | 2 | 4.07 |
| SU | Gregerson, L.Gregerson, Luke >> | 32 | 2016 | R | 90 | 81 | 0 | 5 | 2 | 1.63 | .251 | 0.99 | 5.4 | 3.6 | 11.2 | 93.2 | 56 | 21 | 17 | 4 | 37 | 116 | 0 | 5 | 4 | 0 | 0 | 1 | 4 | 2.29 |
| RP | Blanton, J.Blanton, Joe >> | 36 | 2016 | R | 80 | 93 | 0 | 7 | 5 | 4.84 | .331 | 1.43 | 8.7 | 4.3 | 10.1 | 83.2 | 80 | 46 | 45 | 11 | 40 | 93 | 0 | 2 | 3 | 0 | 0 | 4 | 1 | 4.07 |
| RP | Rondon, H.Rondon, Hector >> | 28 | 2016 | R | 72 | 70 | 0 | 5 | 3 | 3.84 | .284 | 1.15 | 8.6 | 1.8 | 11.3 | 77.1 | 74 | 33 | 33 | 15 | 15 | 97 | 0 | 2 | 2 | 0 | 0 | 3 | 4 | 3.71 |
| RP | Grilli, J.Grilli, Jason >> | 40 | 2016 | R | 55 | 48 | 0 | 2 | 0 | 2.50 | .286 | 1.15 | 6.3 | 4.0 | 9.3 | 54.0 | 38 | 17 | 15 | 6 | 24 | 56 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 3.87 |
| RP | Vincent, N.Vincent, Nick >> | 29 | 2016 | R | 52 | 40 | 0 | 4 | 1 | 3.27 | .295 | 1.19 | 8.3 | 2.4 | 10.8 | 41.1 | 38 | 16 | 15 | 4 | 11 | 49 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 2.90 |