| SP | Darvish, Y.Darvish, Yu >> | 29 | 2016 | R | 91 | 30 | 30 | 5 | 14 | 5.00 | .318 | 1.38 | 9.1 | 3.4 | 10.3 | 169.1 | 171 | 98 | 94 | 20 | 63 | 193 | 0 | 0 | 0 | 0 | 15 | 3 | 7 | 3.43 |
| SP | Straily, D.Straily, Dan >> | 27 | 2016 | R | 82 | 29 | 29 | 6 | 8 | 5.64 | .347 | 1.59 | 10.1 | 4.3 | 7.5 | 154.2 | 172 | 101 | 97 | 22 | 74 | 129 | 0 | 0 | 0 | 0 | 9 | 1 | 1 | 4.64 |
| RP | Thornburg, T.Thornburg, Tyler >> | 27 | 2016 | R | 96 | 97 | 0 | 3 | 5 | 2.26 | .289 | 1.14 | 6.9 | 3.4 | 9.8 | 107.2 | 82 | 31 | 27 | 5 | 41 | 116 | 0 | 9 | 2 | 0 | 0 | 8 | 4 | 2.81 |
| RP | Devenski, C.Devenski, Chris † >> | 25 | 2016 | R | 87 | 91 | 0 | 12 | 9 | 2.76 | .270 | 1.08 | 7.8 | 2.0 | 7.4 | 153.1 | 132 | 50 | 47 | 11 | 34 | 125 | 0 | 7 | 7 | 0 | 0 | 4 | 2 | 3.05 |
| RP | Blanton, J.Blanton, Joe † >> | 36 | 2016 | R | 80 | 63 | 0 | 11 | 4 | 3.56 | .288 | 1.20 | 7.1 | 3.7 | 8.9 | 68.1 | 54 | 28 | 27 | 10 | 28 | 67 | 0 | 6 | 2 | 0 | 0 | 1 | 2 | 4.22 |
| RP | Doolittle, S.Doolittle, Sean >> | 29 | 2016 | L | 68 | 104 | 0 | 2 | 3 | 2.44 | .243 | 0.93 | 5.8 | 2.6 | 8.3 | 81.0 | 52 | 25 | 22 | 6 | 23 | 75 | 0 | 2 | 2 | 0 | 0 | 3 | 2 | 3.07 |
| RP | Torres, C.Torres, Carlos >> | 33 | 2016 | R | 59 | 53 | 0 | 3 | 1 | 2.73 | .314 | 1.32 | 6.6 | 5.3 | 7.2 | 56.0 | 41 | 18 | 17 | 4 | 33 | 45 | 0 | 10 | 4 | 0 | 0 | 3 | 0 | 4.25 |