| SP | Verlander, J.Verlander, Justin >> | 33 | 2016 | R | 98 | 16 | 16 | 3 | 9 | 3.46 | .277 | 1.13 | 8.0 | 2.2 | 9.8 | 112.0 | 99 | 45 | 43 | 13 | 27 | 122 | 2 | 0 | 0 | 2 | 10 | 3 | 1 | 3.13 |
| SP | DeSclafani, A.DeSclafani, Anthony # >> | 26 | 2016 | R | 63 | 15 | 15 | 4 | 7 | 5.21 | .338 | 1.50 | 11.2 | 2.3 | 8.4 | 93.1 | 116 | 55 | 54 | 19 | 24 | 87 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 4.66 |
| SP | McCarthy, B.McCarthy, Brandon >> | 33 | 2016 | R | 63 | 15 | 15 | 3 | 3 | 5.05 | .335 | 1.48 | 8.7 | 4.6 | 10.5 | 62.1 | 60 | 35 | 35 | 8 | 32 | 72 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.00 |
| SP | Bauer, T.Bauer, Trevor >> | 25 | 2016 | R | 56 | 15 | 15 | 5 | 7 | 5.01 | .338 | 1.46 | 9.3 | 3.8 | 9.1 | 79.0 | 82 | 47 | 44 | 13 | 33 | 80 | 0 | 0 | 0 | 0 | 4 | 6 | 5 | 4.59 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 95 | 40 | 0 | 4 | 1 | 3.20 | .296 | 1.17 | 8.0 | 2.6 | 11.7 | 56.1 | 50 | 20 | 20 | 8 | 16 | 73 | 0 | 1 | 0 | 0 | 0 | 5 | 2 | 3.38 |
| RP | Herrera, K.Herrera, Kelvin >> | 26 | 2016 | R | 79 | 38 | 0 | 6 | 3 | 2.80 | .290 | 1.17 | 7.8 | 2.8 | 10.2 | 54.2 | 47 | 17 | 17 | 9 | 17 | 61 | 0 | 0 | 1 | 0 | 0 | 3 | 2 | 4.02 |
| RP | Strickland, H.Strickland, Hunter >> | 27 | 2016 | R | 58 | 37 | 0 | 2 | 1 | 2.85 | .284 | 1.16 | 8.2 | 2.4 | 6.6 | 53.2 | 48 | 19 | 17 | 5 | 14 | 39 | 0 | 3 | 2 | 0 | 0 | 2 | 2 | 3.66 |
| RP | Givens, M.Givens, Mychal >> | 26 | 2016 | R | 49 | 36 | 0 | 4 | 2 | 5.12 | .348 | 1.55 | 8.8 | 5.4 | 9.5 | 38.2 | 37 | 24 | 22 | 5 | 23 | 40 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 4.58 |
| SP | Keuchel, D.Keuchel, Dallas >> | 28 | 2016 | L | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Gausman, K.Gausman, Kevin >> | 25 | 2016 | R | 52 | 4 | 0 | 1 | 0 | 7.11 | .321 | 1.42 | 10.5 | 3.0 | 9.0 | 6.1 | 7 | 5 | 5 | 1 | 2 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.17 |
| SP | Davies, Z.Davies, Zach >> | 23 | 2016 | R | 54 | 34 | 0 | 3 | 2 | 4.04 | .310 | 1.33 | 8.3 | 3.8 | 5.9 | 55.2 | 51 | 25 | 25 | 7 | 23 | 36 | 0 | 6 | 3 | 0 | 0 | 1 | 2 | 4.65 |