| SP | Fulmer, M.Fulmer, Michael # >> | 23 | 2016 | R | 85 | 33 | 33 | 9 | 16 | 4.78 | .321 | 1.38 | 9.6 | 2.9 | 7.4 | 211.0 | 225 | 117 | 112 | 30 | 67 | 173 | 0 | 0 | 0 | 0 | 16 | 7 | 7 | 4.26 |
| SP | Kennedy, I.Kennedy, Ian >> | 32 | 2016 | R | 73 | 32 | 32 | 9 | 12 | 4.32 | .307 | 1.29 | 8.2 | 3.4 | 7.9 | 202.0 | 184 | 101 | 97 | 26 | 77 | 178 | 1 | 0 | 0 | 0 | 18 | 8 | 1 | 4.17 |
| SP | Eickhoff, J.Eickhoff, Jerad >> | 25 | 2016 | R | 72 | 32 | 32 | 11 | 12 | 4.25 | .308 | 1.28 | 8.6 | 3.0 | 8.0 | 201.1 | 192 | 96 | 95 | 33 | 66 | 178 | 0 | 0 | 0 | 0 | 18 | 11 | 0 | 4.51 |
| SP | Shoemaker, M.Shoemaker, Matt # >> | 29 | 2016 | R | 58 | 31 | 31 | 14 | 9 | 3.49 | .298 | 1.22 | 8.9 | 2.2 | 7.5 | 198.2 | 195 | 77 | 77 | 29 | 48 | 166 | 0 | 0 | 0 | 0 | 20 | 10 | 1 | 4.11 |
| RP | Watson, T.Watson, Tony >> | 31 | 2016 | L | 66 | 73 | 0 | 5 | 7 | 3.50 | .284 | 1.17 | 8.2 | 2.3 | 8.0 | 82.1 | 75 | 34 | 32 | 9 | 21 | 73 | 0 | 9 | 7 | 0 | 0 | 2 | 0 | 3.49 |
| RP | Familia, J.Familia, Jeurys >> | 26 | 2016 | R | 53 | 54 | 0 | 5 | 1 | 2.76 | .295 | 1.19 | 7.1 | 3.6 | 9.7 | 62.0 | 49 | 19 | 19 | 4 | 25 | 67 | 0 | 6 | 0 | 0 | 0 | 4 | 0 | 3.08 |
| SP | Keuchel, D.Keuchel, Dallas >> | 28 | 2016 | L | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Gausman, K.Gausman, Kevin >> | 25 | 2016 | R | 52 | 2 | 0 | 1 | 0 | 0.00 | .278 | 0.92 | 6.8 | 2.3 | 9.0 | 4.1 | 3 | 0 | 0 | 0 | 1 | 4 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.50 |
| SP | Richards, G.Richards, Garrett >> | 28 | 2016 | R | 56 | 32 | 0 | 2 | 6 | 4.53 | .335 | 1.49 | 10.1 | 3.4 | 7.9 | 47.2 | 53 | 26 | 24 | 3 | 18 | 41 | 0 | 5 | 2 | 0 | 0 | 1 | 2 | 3.30 |