| SP | Waddell, R.Waddell, Rube † >> | 28 | 1904 | L | 97 | 31 | 30 | 14 | 9 | 3.30 | .289 | 1.20 | 8.1 | 2.7 | 5.7 | 254.0 | 229 | 98 | 93 | 14 | 75 | 160 | 16 | 0 | 0 | 1 | 21 | 5 | 6 | 3.40 |
| SP | McGowan, D.McGowan, Dustin >> | 25 | 2007 | R | 87 | 29 | 29 | 11 | 8 | 4.26 | .333 | 1.49 | 9.6 | 3.8 | 5.7 | 188.0 | 200 | 93 | 89 | 8 | 80 | 119 | 0 | 0 | 0 | 0 | 21 | 1 | 8 | 3.58 |
| SP | McCormick, M.McCormick, Mike >> | 31 | 1969 | L | 68 | 29 | 29 | 11 | 10 | 4.26 | .307 | 1.33 | 8.4 | 3.6 | 3.9 | 192.1 | 179 | 98 | 91 | 17 | 77 | 83 | 1 | 0 | 0 | 0 | 14 | 0 | 3 | 4.49 |
| SP | Perry, G.Perry, Gaylord >> | 39 | 1977 | R | 66 | 29 | 29 | 14 | 7 | 5.40 | .354 | 1.62 | 11.3 | 3.3 | 4.5 | 198.1 | 248 | 125 | 119 | 22 | 73 | 99 | 2 | 0 | 0 | 0 | 10 | 5 | 3 | 4.63 |
| RP | Suarez, R.Suarez, Robert † >> | 31 | 2022 | R | 94 | 74 | 0 | 6 | 4 | 3.11 | .278 | 1.15 | 6.3 | 4.2 | 9.0 | 92.2 | 64 | 33 | 32 | 7 | 43 | 92 | 0 | 13 | 2 | 0 | 0 | 0 | 3 | 3.39 |
| RP | Hanrahan, J.Hanrahan, Joel >> | 31 | 2012 | R | 80 | 16 | 0 | 2 | 2 | 4.73 | .394 | 1.95 | 11.8 | 6.2 | 8.3 | 13.1 | 17 | 7 | 7 | 0 | 9 | 12 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 3.23 |
| RP | Hernandez, X.Hernandez, Xavier >> | 33 | 1998 | R | 71 | 2 | 0 | 1 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 0.0 | 1.2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 48 | 1970 | R | 46 | 17 | 0 | 0 | 0 | 4.30 | .303 | 1.30 | 6.7 | 5.1 | 5.5 | 23.0 | 17 | 11 | 11 | 2 | 13 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.61 |
| SP | Mizell, V.Mizell, Vinegar Bend >> | 28 | 1958 | L | 34 | 4 | 1 | 1 | 2 | 5.95 | .359 | 1.68 | 10.9 | 4.7 | 1.4 | 19.2 | 23 | 17 | 13 | 1 | 10 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.95 |