| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 14 | 14 | 3 | 7 | 4.66 | .329 | 1.45 | 9.5 | 3.6 | 9.3 | 92.2 | 97 | 52 | 48 | 16 | 37 | 95 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 4.47 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 83 | 14 | 14 | 5 | 8 | 3.61 | .274 | 1.11 | 7.3 | 2.7 | 6.2 | 102.1 | 83 | 43 | 41 | 13 | 31 | 70 | 5 | 0 | 0 | 1 | 7 | 2 | 3 | 4.25 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 67 | 13 | 13 | 5 | 4 | 4.20 | .311 | 1.33 | 8.3 | 3.7 | 6.3 | 90.0 | 83 | 45 | 42 | 13 | 37 | 63 | 4 | 0 | 0 | 1 | 7 | 2 | 1 | 4.78 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 64 | 13 | 13 | 3 | 4 | 5.49 | .336 | 1.49 | 11.0 | 2.6 | 6.1 | 83.2 | 101 | 51 | 51 | 10 | 24 | 56 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 4.16 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 39 | 0 | 2 | 5 | 5.60 | .304 | 1.29 | 8.8 | 2.8 | 10.6 | 45.0 | 44 | 28 | 28 | 6 | 14 | 53 | 0 | 5 | 1 | 0 | 0 | 1 | 2 | 3.38 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 16 | 0 | 2 | 0 | 3.60 | .348 | 1.60 | 9.0 | 5.4 | 10.2 | 15.0 | 15 | 6 | 6 | 1 | 9 | 17 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.40 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 75 | 13 | 0 | 1 | 2 | 4.80 | .224 | 0.87 | 5.4 | 2.4 | 9.0 | 15.0 | 9 | 8 | 8 | 4 | 4 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.27 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 12 | 0 | 0 | 1 | 6.55 | .389 | 1.91 | 13.1 | 4.1 | 10.6 | 11.0 | 16 | 8 | 8 | 3 | 5 | 13 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.55 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 55 | 10 | 0 | 0 | 0 | 3.38 | .231 | 0.90 | 6.2 | 2.1 | 9.7 | 13.1 | 9 | 5 | 5 | 2 | 3 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.54 |