| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 34 | 34 | 13 | 16 | 4.22 | .301 | 1.26 | 8.5 | 2.9 | 7.8 | 253.2 | 238 | 137 | 119 | 34 | 82 | 220 | 11 | 0 | 0 | 1 | 16 | 7 | 6 | 4.06 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 33 | 33 | 9 | 13 | 4.43 | .296 | 1.24 | 8.1 | 3.1 | 8.3 | 211.1 | 190 | 107 | 104 | 38 | 73 | 195 | 0 | 0 | 0 | 0 | 17 | 4 | 3 | 4.59 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 31 | 31 | 12 | 10 | 4.33 | .326 | 1.43 | 10.0 | 3.0 | 7.3 | 207.2 | 229 | 105 | 100 | 23 | 69 | 167 | 4 | 0 | 0 | 1 | 16 | 3 | 2 | 3.87 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 32 | 32 | 12 | 16 | 5.16 | .337 | 1.51 | 10.1 | 3.5 | 5.0 | 199.0 | 224 | 117 | 114 | 29 | 77 | 111 | 9 | 0 | 0 | 0 | 14 | 3 | 1 | 4.98 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 31 | 31 | 12 | 16 | 5.42 | .314 | 1.35 | 9.5 | 2.7 | 4.7 | 220.2 | 231 | 144 | 133 | 32 | 67 | 116 | 8 | 0 | 0 | 0 | 9 | 5 | 2 | 4.82 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 82 | 0 | 4 | 3 | 3.29 | .290 | 1.23 | 7.7 | 3.4 | 7.0 | 109.1 | 93 | 41 | 40 | 5 | 41 | 85 | 0 | 11 | 5 | 0 | 0 | 0 | 1 | 3.17 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 68 | 0 | 8 | 3 | 4.32 | .297 | 1.25 | 8.0 | 3.3 | 7.3 | 81.1 | 72 | 41 | 39 | 13 | 30 | 66 | 0 | 9 | 2 | 0 | 0 | 1 | 0 | 4.60 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 51 | 0 | 2 | 2 | 4.60 | .297 | 1.27 | 8.6 | 3.0 | 7.2 | 60.2 | 57 | 31 | 31 | 11 | 20 | 48 | 0 | 5 | 2 | 0 | 0 | 0 | 3 | 4.78 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 20 | 0 | 1 | 0 | 3.09 | .239 | 0.94 | 4.7 | 3.9 | 5.9 | 23.1 | 12 | 8 | 8 | 4 | 10 | 15 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 5.26 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 7 | 1 | 1 | 2 | 5.09 | .312 | 1.36 | 9.5 | 3.2 | 5.3 | 17.2 | 18 | 10 | 10 | 2 | 6 | 10 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 4.41 |