| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 34 | 34 | 14 | 13 | 4.52 | .302 | 1.28 | 8.9 | 2.7 | 4.6 | 250.2 | 248 | 132 | 126 | 25 | 74 | 129 | 8 | 0 | 0 | 2 | 17 | 3 | 5 | 4.19 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 33 | 33 | 12 | 14 | 4.50 | .310 | 1.33 | 7.7 | 4.3 | 8.3 | 218.0 | 187 | 118 | 109 | 30 | 104 | 200 | 3 | 0 | 0 | 2 | 20 | 3 | 3 | 4.43 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 32 | 32 | 8 | 17 | 5.19 | .336 | 1.48 | 9.4 | 4.0 | 4.1 | 223.2 | 234 | 141 | 129 | 23 | 98 | 101 | 4 | 0 | 0 | 0 | 12 | 7 | 1 | 4.85 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 32 | 32 | 9 | 21 | 4.69 | .305 | 1.31 | 8.7 | 3.1 | 4.8 | 239.2 | 231 | 131 | 125 | 28 | 83 | 128 | 16 | 0 | 0 | 1 | 14 | 2 | 7 | 4.52 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 31 | 31 | 11 | 15 | 4.98 | .329 | 1.46 | 9.6 | 3.6 | 6.4 | 227.2 | 241 | 144 | 126 | 38 | 91 | 162 | 8 | 0 | 0 | 1 | 10 | 3 | 11 | 4.99 |
| RP | Kimbrel, C.Kimbrel, Craig # >> | 24 | 2012 | R | 100 | 77 | 0 | 6 | 6 | 4.82 | .288 | 1.19 | 7.6 | 3.2 | 9.5 | 106.1 | 89 | 58 | 57 | 15 | 38 | 112 | 0 | 6 | 7 | 0 | 0 | 2 | 6 | 3.86 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 61 | 0 | 4 | 3 | 4.52 | .330 | 1.48 | 8.6 | 4.9 | 11.3 | 63.2 | 60 | 32 | 32 | 6 | 34 | 79 | 0 | 6 | 1 | 0 | 0 | 0 | 1 | 3.35 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 16 | 0 | 0 | 1 | 4.02 | .329 | 1.47 | 6.6 | 7.2 | 11.4 | 15.2 | 11 | 8 | 7 | 1 | 12 | 19 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.73 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 22 | 0 | 0 | 2 | 6.04 | .350 | 1.62 | 10.1 | 4.7 | 6.8 | 25.1 | 28 | 18 | 17 | 7 | 13 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.68 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 0.0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |