| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 14 | 14 | 1 | 6 | 4.43 | .297 | 1.25 | 8.1 | 3.2 | 7.2 | 91.1 | 82 | 47 | 45 | 12 | 32 | 73 | 0 | 0 | 0 | 0 | 10 | 2 | 2 | 4.23 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 12 | 12 | 3 | 8 | 5.27 | .309 | 1.33 | 9.1 | 2.9 | 8.4 | 71.2 | 72 | 43 | 42 | 11 | 23 | 66 | 3 | 0 | 0 | 0 | 6 | 1 | 3 | 4.17 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 14 | 14 | 4 | 6 | 4.51 | .318 | 1.38 | 9.2 | 3.3 | 5.4 | 105.2 | 107 | 55 | 53 | 13 | 39 | 63 | 4 | 0 | 0 | 0 | 4 | 2 | 3 | 4.58 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 13 | 12 | 4 | 5 | 5.47 | .344 | 1.55 | 10.0 | 4.1 | 4.4 | 80.2 | 89 | 50 | 49 | 14 | 36 | 39 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 5.73 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 35 | 0 | 5 | 0 | 1.74 | .176 | 0.64 | 3.7 | 2.2 | 10.4 | 46.2 | 19 | 9 | 9 | 7 | 11 | 53 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 3.39 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 26 | 0 | 3 | 2 | 2.84 | .296 | 1.17 | 9.3 | 1.5 | 8.7 | 31.2 | 32 | 12 | 10 | 4 | 5 | 30 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 3.52 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 22 | 0 | 2 | 4 | 3.92 | .303 | 1.31 | 9.9 | 2.3 | 7.7 | 20.2 | 22 | 10 | 9 | 3 | 5 | 17 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 17 | 0 | 1 | 0 | 2.65 | .320 | 1.41 | 5.8 | 6.9 | 12.2 | 17.0 | 11 | 5 | 5 | 1 | 13 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.35 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 14 | 0 | 3 | 0 | 6.43 | .364 | 1.64 | 7.7 | 7.1 | 7.1 | 14.0 | 12 | 10 | 10 | 1 | 11 | 11 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.93 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 6 | 2 | 1 | 0 | 3.79 | .345 | 1.58 | 11.4 | 2.8 | 9.0 | 19.0 | 24 | 8 | 8 | 1 | 6 | 19 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 2.63 |