| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 37 | 37 | 14 | 15 | 3.70 | .288 | 1.18 | 6.9 | 3.7 | 7.7 | 245.2 | 189 | 102 | 101 | 23 | 102 | 209 | 5 | 0 | 0 | 1 | 24 | 7 | 1 | 3.85 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 36 | 36 | 13 | 13 | 4.38 | .291 | 1.21 | 8.5 | 2.4 | 3.2 | 232.0 | 218 | 119 | 113 | 28 | 62 | 82 | 8 | 0 | 0 | 2 | 18 | 5 | 2 | 4.73 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 34 | 33 | 12 | 13 | 4.69 | .326 | 1.44 | 8.9 | 4.1 | 7.2 | 186.0 | 183 | 104 | 97 | 29 | 85 | 149 | 1 | 0 | 0 | 0 | 15 | 2 | 2 | 4.83 |
| SP | Waddell, R.Waddell, Rube # >> | 29 | 1905 | L | 67 | 32 | 31 | 10 | 11 | 4.59 | .297 | 1.25 | 8.9 | 2.3 | 4.9 | 190.0 | 188 | 102 | 97 | 17 | 49 | 103 | 6 | 0 | 0 | 3 | 13 | 4 | 7 | 3.92 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 103 | 0 | 6 | 8 | 4.41 | .308 | 1.30 | 6.9 | 4.9 | 9.5 | 132.2 | 101 | 66 | 65 | 13 | 72 | 140 | 0 | 7 | 7 | 0 | 0 | 4 | 14 | 3.89 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 92 | 0 | 5 | 7 | 4.64 | .325 | 1.43 | 9.5 | 3.4 | 8.2 | 99.0 | 105 | 51 | 51 | 16 | 37 | 90 | 0 | 9 | 7 | 0 | 0 | 1 | 0 | 4.43 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 81 | 0 | 5 | 3 | 3.64 | .308 | 1.33 | 6.6 | 5.4 | 7.3 | 89.0 | 65 | 37 | 36 | 9 | 53 | 72 | 0 | 6 | 2 | 0 | 0 | 1 | 9 | 4.52 |
| RP | Messersmith, A.Messersmith, Andy † >> | 23 | 1968 | R | 57 | 66 | 0 | 7 | 5 | 3.06 | .291 | 1.23 | 6.8 | 4.3 | 5.9 | 103.0 | 78 | 37 | 35 | 9 | 49 | 67 | 0 | 10 | 1 | 0 | 0 | 0 | 4 | 4.26 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 47 | 0 | 4 | 4 | 3.82 | .243 | 0.93 | 5.8 | 2.7 | 7.8 | 61.1 | 39 | 26 | 26 | 5 | 18 | 53 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.31 |