| SP | Scherzer, M.Scherzer, Max >> | 25 | 2023 | R | 96 | 27 | 27 | 11 | 12 | 4.98 | .300 | 1.26 | 8.1 | 3.3 | 7.6 | 193.1 | 173 | 110 | 107 | 22 | 71 | 164 | 4 | 0 | 0 | 2 | 10 | 5 | 0 | 3.96 |
| SP | Arrieta, J.Arrieta, Jake # >> | 25 | 2015 | R | 80 | 27 | 27 | 10 | 12 | 4.99 | .293 | 1.21 | 8.9 | 2.0 | 6.3 | 191.0 | 189 | 111 | 106 | 39 | 43 | 134 | 10 | 0 | 0 | 2 | 13 | 6 | 1 | 5.02 |
| SP | McKenzie, T.McKenzie, Triston # >> | 25 | 2022 | R | 67 | 27 | 27 | 14 | 7 | 5.62 | .322 | 1.41 | 9.9 | 2.7 | 5.8 | 181.0 | 200 | 117 | 113 | 36 | 55 | 117 | 7 | 0 | 0 | 0 | 12 | 3 | 6 | 5.25 |
| SP | Severino, L.Severino, Luis >> | 25 | 2017 | R | 57 | 26 | 26 | 6 | 10 | 7.91 | .354 | 1.61 | 11.6 | 2.9 | 8.0 | 160.1 | 206 | 147 | 141 | 40 | 52 | 143 | 2 | 0 | 0 | 0 | 2 | 6 | 5 | 5.55 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 41 | 22 | 22 | 9 | 10 | 7.72 | .373 | 1.75 | 11.4 | 4.4 | 5.6 | 134.0 | 169 | 119 | 115 | 36 | 66 | 84 | 4 | 0 | 0 | 0 | 5 | 4 | 4 | 6.81 |
| RP | Uehara, K.Uehara, Koji >> | 25 | 2012 | R | 93 | 67 | 0 | 7 | 2 | 2.94 | .259 | 1.04 | 7.3 | 2.0 | 8.6 | 101.0 | 82 | 39 | 33 | 9 | 23 | 96 | 0 | 10 | 1 | 0 | 0 | 1 | 2 | 2.97 |
| RP | Valdes, R.Valdes, Raul >> | 25 | 2012 | L | 91 | 42 | 0 | 6 | 4 | 4.29 | .300 | 1.27 | 7.0 | 4.4 | 8.1 | 63.0 | 49 | 31 | 30 | 7 | 31 | 57 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.16 |
| RP | Castillo, J.Castillo, Jose >> | 25 | 2018 | L | 80 | 26 | 0 | 2 | 3 | 4.38 | .259 | 1.05 | 6.9 | 2.5 | 7.4 | 39.0 | 30 | 20 | 19 | 4 | 11 | 32 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 3.54 |
| RP | Lloyd, G.Lloyd, Graeme >> | 25 | 1998 | L | 62 | 15 | 0 | 2 | 1 | 4.98 | .261 | 1.06 | 6.9 | 3.0 | 3.4 | 21.2 | 16 | 12 | 12 | 4 | 7 | 8 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 5.71 |
| RP | Hudson, D.Hudson, Daniel >> | 25 | 2021 | R | 59 | 10 | 0 | 0 | 1 | 6.97 | .367 | 1.74 | 10.8 | 5.4 | 9.9 | 10.1 | 12 | 8 | 8 | 3 | 6 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 6.50 |
| RP | Madson, R.Madson, Ryan >> | 25 | 2017 | R | 42 | 4 | 0 | 0 | 0 | 6.35 | .320 | 1.41 | 10.8 | 3.6 | 3.6 | 5.2 | 6 | 4 | 4 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| RP | Minter, A.Minter, A.J. >> | 25 | 2022 | L | 30 | 8 | 0 | 0 | 0 | 4.85 | .328 | 1.46 | 9.7 | 3.5 | 7.6 | 13.0 | 14 | 7 | 7 | 2 | 5 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.46 |