| SP | Martinez, P.Martinez, Pedro >> | 25 | 2000 | R | 98 | 27 | 27 | 11 | 10 | 4.47 | .281 | 1.14 | 8.3 | 2.0 | 8.7 | 169.0 | 156 | 90 | 84 | 21 | 37 | 163 | 10 | 0 | 0 | 4 | 11 | 5 | 3 | 3.43 |
| SP | Maddux, G.Maddux, Greg # >> | 25 | 1995 | R | 76 | 27 | 27 | 8 | 15 | 4.87 | .308 | 1.31 | 9.6 | 2.2 | 5.3 | 159.0 | 169 | 92 | 86 | 19 | 39 | 94 | 9 | 0 | 0 | 3 | 9 | 4 | 0 | 4.18 |
| SP | McLain, D.McLain, Denny >> | 25 | 1968 | R | 57 | 26 | 26 | 12 | 5 | 6.07 | .313 | 1.36 | 10.4 | 1.9 | 4.5 | 145.1 | 167 | 102 | 98 | 34 | 30 | 72 | 6 | 0 | 0 | 0 | 6 | 2 | 1 | 5.72 |
| SP | Pfiester, J.Pfiester, Jack >> | 25 | 1906 | L | 46 | 22 | 22 | 6 | 12 | 6.21 | .320 | 1.39 | 9.6 | 2.9 | 5.5 | 120.1 | 128 | 88 | 83 | 29 | 39 | 73 | 6 | 0 | 0 | 1 | 6 | 3 | 2 | 5.98 |
| RP | Feliz, N.Feliz, Neftali >> | 25 | 2009 | R | 100 | 57 | 0 | 5 | 2 | 2.32 | .232 | 0.88 | 6.3 | 1.7 | 10.4 | 89.1 | 62 | 25 | 23 | 7 | 17 | 103 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 2.35 |
| RP | Green, C.Green, Chad # >> | 25 | 2017 | R | 93 | 41 | 0 | 3 | 3 | 5.28 | .293 | 1.21 | 6.4 | 4.5 | 9.0 | 58.0 | 41 | 35 | 34 | 10 | 29 | 58 | 0 | 4 | 1 | 0 | 0 | 2 | 2 | 4.84 |
| RP | Wagner, B.Wagner, Billy >> | 25 | 1999 | L | 73 | 58 | 0 | 4 | 1 | 4.53 | .274 | 1.11 | 6.7 | 3.4 | 7.7 | 47.2 | 35 | 25 | 24 | 6 | 18 | 40 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.17 |
| RP | Osuna, R.Osuna, Roberto >> | 25 | 2019 | R | 44 | 18 | 0 | 5 | 1 | 4.88 | .339 | 1.54 | 10.9 | 3.0 | 7.9 | 24.0 | 29 | 13 | 13 | 2 | 8 | 21 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.33 |
| RP | Janssen, C.Janssen, Casey >> | 25 | 2012 | R | 32 | 13 | 0 | 0 | 1 | 3.24 | .254 | 1.02 | 6.2 | 3.4 | 10.7 | 16.2 | 11 | 6 | 6 | 2 | 6 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.38 |
| RP | Smoltz, J.Smoltz, John >> | 25 | 2003 | R | 25 | 15 | 0 | 1 | 0 | 5.29 | .301 | 1.29 | 8.5 | 3.2 | 7.4 | 17.0 | 16 | 10 | 10 | 5 | 6 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.24 |