| SP | Beachy, B.Beachy, Brandon >> | 25 | 2012 | R | 95 | 27 | 27 | 3 | 18 | 6.29 | .333 | 1.48 | 10.1 | 3.2 | 5.3 | 150.1 | 169 | 108 | 105 | 28 | 53 | 89 | 2 | 0 | 0 | 0 | 4 | 3 | 9 | 5.36 |
| SP | Kershaw, C.Kershaw, Clayton # >> | 25 | 2015 | L | 80 | 27 | 27 | 15 | 6 | 4.58 | .303 | 1.30 | 8.9 | 2.8 | 9.1 | 171.0 | 169 | 90 | 87 | 22 | 53 | 172 | 5 | 0 | 0 | 1 | 14 | 1 | 3 | 3.61 |
| SP | Skubal, T.Skubal, Tarik >> | 25 | 2025 | L | 71 | 27 | 27 | 4 | 11 | 9.00 | .394 | 1.93 | 14.3 | 3.1 | 8.7 | 115.0 | 183 | 121 | 115 | 31 | 39 | 111 | 1 | 0 | 0 | 0 | 5 | 2 | 1 | 5.64 |
| SP | Johnson, R.Johnson, Randy >> | 25 | 1995 | L | 52 | 26 | 26 | 12 | 8 | 4.29 | .295 | 1.24 | 8.1 | 3.0 | 7.8 | 170.0 | 153 | 88 | 81 | 25 | 57 | 148 | 9 | 0 | 0 | 1 | 14 | 3 | 3 | 4.23 |
| SP | De La Rosa, J.De La Rosa, Jorge >> | 25 | 2011 | L | 37 | 22 | 22 | 8 | 5 | 6.45 | .334 | 1.49 | 9.8 | 3.6 | 7.7 | 114.1 | 124 | 84 | 82 | 27 | 46 | 98 | 1 | 0 | 0 | 0 | 6 | 2 | 5 | 5.62 |
| RP | Rainey, T.Rainey, Tanner >> | 25 | 2020 | R | 100 | 74 | 0 | 5 | 2 | 2.60 | .278 | 1.14 | 6.4 | 3.9 | 7.8 | 90.0 | 64 | 27 | 26 | 4 | 39 | 78 | 0 | 4 | 1 | 0 | 0 | 1 | 11 | 3.18 |
| RP | Reardon, J.Reardon, Jeff >> | 25 | 1981 | R | 85 | 71 | 0 | 1 | 1 | 4.48 | .292 | 1.21 | 7.9 | 3.0 | 5.9 | 66.1 | 58 | 34 | 33 | 9 | 22 | 43 | 0 | 6 | 2 | 0 | 0 | 2 | 2 | 4.56 |
| RP | Chapman, A.Chapman, Aroldis >> | 25 | 2012 | L | 77 | 70 | 0 | 2 | 3 | 3.52 | .290 | 1.20 | 6.6 | 4.3 | 11.5 | 71.2 | 52 | 32 | 28 | 4 | 34 | 91 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 2.69 |
| RP | Rodríguez, R.Rodríguez, Randy >> | 25 | 2025 | R | 55 | 50 | 0 | 2 | 1 | 3.16 | .316 | 1.38 | 8.1 | 4.5 | 9.9 | 42.2 | 38 | 17 | 15 | 1 | 21 | 46 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 2.62 |
| RP | Scott, T.Scott, Tanner >> | 25 | 2023 | L | 26 | 28 | 0 | 1 | 2 | 6.48 | .359 | 1.68 | 10.8 | 4.3 | 10.1 | 25.0 | 30 | 19 | 18 | 3 | 12 | 28 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.76 |
| RP | Herget, J.Herget, Jimmy >> | 25 | 2022 | R | 18 | 39 | 0 | 4 | 5 | 3.78 | .309 | 1.32 | 6.1 | 5.8 | 6.7 | 50.0 | 34 | 24 | 21 | 3 | 32 | 37 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 4.28 |
| SP | Jimenez, U.Jimenez, Ubaldo >> | 25 | 2010 | R | 23 | 10 | 0 | 0 | 4 | 7.88 | .333 | 1.50 | 10.1 | 3.4 | 4.5 | 16.0 | 18 | 14 | 14 | 5 | 6 | 8 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.19 |