| SP | Burnes, C.Burnes, Corbin # >> | 27 | 2022 | R | 97 | 21 | 21 | 9 | 9 | 4.20 | .293 | 1.22 | 8.6 | 2.4 | 7.4 | 126.1 | 121 | 62 | 59 | 6 | 33 | 103 | 0 | 0 | 0 | 0 | 11 | 3 | 5 | 2.84 |
| SP | deGrom, J.deGrom, Jacob † >> | 30 | 2018 | R | 99 | 21 | 21 | 8 | 7 | 2.25 | .257 | 1.02 | 7.3 | 2.0 | 7.3 | 156.1 | 126 | 39 | 39 | 8 | 34 | 127 | 3 | 0 | 0 | 0 | 19 | 2 | 3 | 2.73 |
| SP | Kershaw, C.Kershaw, Clayton >> | 24 | 2012 | L | 92 | 21 | 21 | 9 | 5 | 2.22 | .266 | 1.06 | 6.2 | 3.3 | 7.0 | 154.1 | 106 | 43 | 38 | 10 | 57 | 120 | 3 | 0 | 0 | 1 | 19 | 5 | 4 | 3.49 |
| RP | Dotel, O.Dotel, Octavio >> | 30 | 2003 | R | 85 | 53 | 0 | 3 | 3 | 2.86 | .287 | 1.17 | 6.3 | 4.3 | 8.3 | 63.0 | 44 | 20 | 20 | 3 | 30 | 58 | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 3.30 |
| RP | Cishek, S.Cishek, Steven >> | 29 | 2015 | R | 17 | 27 | 0 | 3 | 0 | 3.54 | .396 | 1.93 | 10.6 | 6.8 | 7.1 | 28.0 | 33 | 14 | 11 | 3 | 21 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 5.18 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 99 | 47 | 0 | 2 | 4 | 2.55 | .271 | 1.07 | 7.9 | 1.8 | 7.3 | 49.1 | 43 | 16 | 14 | 0 | 10 | 40 | 0 | 28 | 2 | 0 | 0 | 2 | 1 | 2.10 |
| SU | Kimbrel, C.Kimbrel, Craig # >> | 26 | 2014 | R | 95 | 45 | 0 | 0 | 2 | 4.75 | .324 | 1.37 | 7.9 | 4.6 | 10.8 | 41.2 | 36 | 24 | 22 | 3 | 21 | 49 | 0 | 2 | 2 | 0 | 0 | 3 | 2 | 3.32 |
| SP | Downing, A.Downing, Al >> | 26 | 1967 | L | 80 | 7 | 0 | 2 | 1 | 2.00 | .299 | 1.22 | 8.0 | 3.0 | 2.5 | 18.0 | 16 | 5 | 4 | 2 | 6 | 5 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.06 |