| SP | Reulbach, E.Reulbach, Ed >> | 27 | 1909 | R | 83 | 24 | 24 | 7 | 12 | 4.49 | .317 | 1.37 | 8.7 | 3.7 | 4.5 | 146.1 | 141 | 79 | 73 | 9 | 60 | 73 | 1 | 0 | 0 | 0 | 12 | 3 | 2 | 4.10 |
| SP | Weaver, J.Weaver, Jered >> | 28 | 2010 | R | 80 | 24 | 24 | 7 | 10 | 3.25 | .272 | 1.12 | 7.3 | 2.8 | 7.4 | 149.2 | 121 | 59 | 54 | 14 | 46 | 123 | 1 | 0 | 0 | 0 | 13 | 1 | 3 | 3.52 |
| SP | Verlander, J.Verlander, Justin >> | 27 | 2010 | R | 54 | 24 | 24 | 11 | 6 | 3.34 | .284 | 1.13 | 7.3 | 2.9 | 5.0 | 161.2 | 131 | 66 | 60 | 10 | 52 | 90 | 4 | 0 | 0 | 0 | 18 | 9 | 5 | 3.83 |
| SP | Strasburg, S.Strasburg, Stephen >> | 25 | 2014 | R | 59 | 24 | 24 | 10 | 8 | 4.16 | .320 | 1.39 | 9.4 | 3.2 | 8.4 | 145.0 | 151 | 79 | 67 | 16 | 51 | 135 | 0 | 0 | 0 | 0 | 15 | 3 | 2 | 3.69 |
| RP | Helsley, R.Helsley, Ryan >> | 28 | 2023 | R | 82 | 61 | 0 | 2 | 1 | 2.41 | .297 | 1.25 | 6.3 | 5.0 | 9.2 | 56.0 | 39 | 16 | 15 | 3 | 31 | 57 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 3.38 |
| RP | Perkins, G.Perkins, Glen >> | 28 | 2011 | L | 37 | 44 | 0 | 3 | 2 | 3.11 | .323 | 1.38 | 8.3 | 4.4 | 7.1 | 37.2 | 34 | 13 | 13 | 1 | 18 | 29 | 0 | 2 | 2 | 0 | 0 | 2 | 1 | 3.41 |
| RP | Guerrier, M.Guerrier, Matt >> | 30 | 2008 | R | 7 | 54 | 0 | 2 | 2 | 5.51 | .293 | 1.18 | 6.5 | 4.3 | 5.2 | 50.2 | 36 | 33 | 31 | 6 | 24 | 29 | 0 | 4 | 1 | 0 | 0 | 3 | 1 | 5.02 |
| SU | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 90 | 49 | 0 | 0 | 3 | 4.74 | .330 | 1.48 | 8.4 | 5.0 | 8.6 | 49.1 | 46 | 27 | 26 | 5 | 27 | 47 | 0 | 5 | 5 | 0 | 0 | 0 | 3 | 4.06 |
| CL | Clippard, T.Clippard, Tyler † >> | 28 | 2013 | R | 92 | 49 | 0 | 3 | 6 | 2.72 | .262 | 1.07 | 5.5 | 4.2 | 10.5 | 49.2 | 30 | 17 | 15 | 4 | 23 | 57 | 0 | 26 | 3 | 0 | 0 | 0 | 2 | 3.14 |
| SP | Halladay, R.Halladay, Roy >> | 26 | 2003 | R | 58 | 7 | 0 | 1 | 3 | 3.29 | .305 | 1.32 | 9.7 | 2.8 | 9.0 | 13.2 | 14 | 7 | 5 | 3 | 4 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.92 |