| SP | Buehler, W.Buehler, Walker >> | 24 | 2019 | R | 92 | 19 | 19 | 5 | 11 | 3.80 | .311 | 1.36 | 9.7 | 2.5 | 7.9 | 111.1 | 120 | 55 | 47 | 11 | 31 | 98 | 0 | 0 | 0 | 0 | 12 | 0 | 3 | 3.36 |
| SP | Eckersley, D.Eckersley, Dennis >> | 22 | 1976 | R | 80 | 18 | 18 | 4 | 9 | 3.20 | .321 | 1.38 | 8.4 | 4.1 | 7.0 | 101.1 | 94 | 43 | 36 | 5 | 46 | 79 | 0 | 0 | 0 | 0 | 7 | 4 | 1 | 3.56 |
| SP | Kluber, C.Kluber, Corey >> | 27 | 2013 | R | 42 | 17 | 17 | 5 | 4 | 5.96 | .331 | 1.46 | 10.5 | 2.6 | 5.4 | 83.0 | 97 | 55 | 55 | 6 | 24 | 50 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 3.67 |
| SP | Arrieta, J.Arrieta, Jake >> | 25 | 2011 | R | 31 | 16 | 16 | 2 | 7 | 4.71 | .332 | 1.46 | 9.1 | 4.1 | 5.9 | 80.1 | 81 | 47 | 42 | 5 | 36 | 52 | 0 | 0 | 0 | 0 | 5 | 3 | 0 | 3.98 |
| RP | LaRoche, D.LaRoche, Dave >> | 23 | 1971 | L | 66 | 47 | 0 | 3 | 4 | 3.81 | .292 | 1.22 | 8.2 | 2.7 | 6.6 | 59.0 | 54 | 28 | 25 | 4 | 18 | 43 | 0 | 0 | 3 | 0 | 0 | 1 | 4 | 3.39 |
| RP | Rincon, R.Rincon, Ricardo >> | 28 | 1998 | L | 58 | 43 | 0 | 1 | 2 | 1.83 | .257 | 1.02 | 5.3 | 3.8 | 4.7 | 54.0 | 32 | 13 | 11 | 2 | 23 | 28 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.78 |
| RP | Minter, A.Minter, A.J. >> | 24 | 2018 | L | 41 | 30 | 0 | 2 | 1 | 3.53 | .277 | 1.15 | 8.2 | 2.3 | 9.0 | 35.2 | 32 | 14 | 14 | 2 | 9 | 35 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 2.51 |
| SU | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 90 | 40 | 0 | 1 | 1 | 3.44 | .321 | 1.39 | 7.8 | 5.0 | 10.3 | 36.2 | 31 | 15 | 14 | 1 | 20 | 41 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 2.83 |
| CL | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 94 | 34 | 0 | 4 | 1 | 2.67 | .263 | 1.07 | 6.0 | 3.8 | 7.6 | 33.2 | 22 | 12 | 10 | 2 | 14 | 28 | 0 | 17 | 2 | 0 | 0 | 0 | 0 | 3.36 |
| SP | Roberts, R.Roberts, Robin >> | 23 | 1949 | R | 28 | 8 | 0 | 0 | 0 | 2.92 | .260 | 1.05 | 6.0 | 3.8 | 3.8 | 12.1 | 8 | 4 | 4 | 1 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 |