| SP | Kluber, C.Kluber, Corey >> | 30 | 2016 | R | 87 | 24 | 24 | 7 | 13 | 4.33 | .318 | 1.38 | 8.9 | 3.6 | 7.3 | 147.2 | 145 | 76 | 71 | 14 | 59 | 119 | 1 | 0 | 0 | 0 | 12 | 3 | 3 | 3.88 |
| SP | Roberts, R.Roberts, Robin >> | 26 | 1952 | R | 70 | 24 | 24 | 8 | 8 | 3.88 | .301 | 1.29 | 9.1 | 2.6 | 3.7 | 169.1 | 170 | 86 | 73 | 13 | 48 | 69 | 4 | 0 | 0 | 1 | 14 | 1 | 2 | 4.05 |
| SP | Eckersley, D.Eckersley, Dennis >> | 25 | 1979 | R | 32 | 24 | 24 | 5 | 13 | 6.81 | .344 | 1.56 | 10.6 | 3.5 | 5.0 | 120.1 | 141 | 103 | 91 | 20 | 47 | 66 | 1 | 0 | 0 | 0 | 8 | 1 | 0 | 5.27 |
| RP | Gregerson, L.Gregerson, Luke >> | 29 | 2013 | R | 74 | 68 | 0 | 4 | 1 | 2.11 | .241 | 0.95 | 5.3 | 3.2 | 5.3 | 81.0 | 48 | 23 | 19 | 4 | 29 | 48 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3.53 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 25 | 2007 | R | 55 | 64 | 0 | 6 | 1 | 1.87 | .258 | 1.02 | 5.2 | 4.1 | 9.8 | 57.2 | 33 | 12 | 12 | 2 | 26 | 62 | 0 | 2 | 0 | 0 | 0 | 1 | 3 | 2.70 |
| RP | Minter, A.Minter, A.J. >> | 27 | 2021 | L | 41 | 70 | 0 | 4 | 3 | 2.94 | .274 | 1.13 | 6.9 | 3.4 | 5.5 | 64.1 | 49 | 25 | 21 | 5 | 24 | 39 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.92 |
| RP | Rincon, R.Rincon, Ricardo >> | 31 | 2001 | L | 49 | 47 | 0 | 3 | 1 | 2.16 | .257 | 1.00 | 6.3 | 2.7 | 4.5 | 50.0 | 35 | 13 | 12 | 3 | 15 | 25 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.80 |
| RP | Stanton, M.Stanton, Mike >> | 26 | 1993 | L | 16 | 27 | 0 | 1 | 0 | 3.41 | .299 | 1.28 | 7.9 | 3.7 | 4.2 | 34.1 | 30 | 15 | 13 | 1 | 14 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.68 |
| SP | Arrieta, J.Arrieta, Jake >> | 28 | 2014 | R | 95 | 23 | 23 | 10 | 6 | 2.56 | .269 | 1.09 | 6.9 | 3.0 | 7.1 | 151.1 | 115 | 46 | 43 | 4 | 50 | 119 | 1 | 0 | 0 | 1 | 17 | 2 | 5 | 2.80 |
| SP | Buehler, W.Buehler, Walker >> | 27 | 2022 | R | 20 | 9 | 0 | 1 | 5 | 3.05 | .262 | 1.06 | 7.7 | 2.3 | 2.7 | 20.2 | 17 | 10 | 7 | 2 | 5 | 6 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.45 |
| CL | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 97 | 51 | 0 | 1 | 4 | 2.73 | .255 | 1.01 | 6.6 | 2.6 | 9.0 | 52.2 | 38 | 16 | 16 | 2 | 15 | 52 | 0 | 25 | 4 | 0 | 0 | 1 | 1 | 2.42 |