| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 99 | 21 | 21 | 10 | 8 | 2.56 | .238 | 0.92 | 5.7 | 2.6 | 7.3 | 158.0 | 100 | 46 | 45 | 9 | 46 | 129 | 5 | 0 | 0 | 2 | 16 | 2 | 0 | 3.02 |
| SP | Seaver, T.Seaver, Tom † >> | 27 | 1971 | R | 94 | 21 | 21 | 11 | 5 | 3.01 | .276 | 1.13 | 7.4 | 2.8 | 7.6 | 149.2 | 122 | 54 | 50 | 3 | 47 | 126 | 8 | 0 | 0 | 1 | 14 | 2 | 2 | 2.56 |
| SP | McLain, D.McLain, Denny † >> | 24 | 1968 | R | 97 | 21 | 21 | 11 | 6 | 2.47 | .247 | 0.98 | 6.7 | 2.2 | 5.5 | 156.2 | 116 | 44 | 43 | 8 | 38 | 96 | 4 | 0 | 0 | 1 | 15 | 0 | 3 | 3.17 |
| SP | Lincecum, T.Lincecum, Tim >> | 27 | 2011 | R | 50 | 20 | 20 | 5 | 11 | 4.86 | .321 | 1.37 | 7.7 | 4.7 | 6.1 | 109.1 | 93 | 62 | 59 | 5 | 57 | 74 | 1 | 0 | 0 | 1 | 9 | 5 | 4 | 3.94 |
| RP | Doolittle, S.Doolittle, Sean >> | 29 | 2016 | L | 64 | 28 | 0 | 2 | 0 | 1.93 | .277 | 1.13 | 7.8 | 2.4 | 9.5 | 37.1 | 32 | 8 | 8 | 1 | 10 | 39 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 2.14 |
| RP | Williamson, S.Williamson, Scott >> | 27 | 2003 | R | 27 | 21 | 0 | 4 | 0 | 2.25 | .258 | 1.04 | 7.1 | 2.3 | 8.3 | 24.0 | 19 | 6 | 6 | 1 | 6 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.46 |
| CL | Franco, J.Franco, John >> | 28 | 1988 | L | 73 | 46 | 0 | 1 | 7 | 4.06 | .318 | 1.40 | 9.2 | 3.5 | 3.3 | 44.1 | 45 | 20 | 20 | 2 | 17 | 16 | 0 | 23 | 6 | 0 | 0 | 0 | 0 | 4.02 |