| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 99 | 24 | 24 | 11 | 9 | 2.61 | .239 | 0.93 | 5.6 | 2.8 | 7.6 | 179.1 | 112 | 53 | 52 | 11 | 55 | 151 | 5 | 0 | 0 | 2 | 18 | 2 | 0 | 3.07 |
| SP | Seaver, T.Seaver, Tom † >> | 27 | 1971 | R | 94 | 24 | 24 | 14 | 5 | 2.97 | .279 | 1.15 | 7.5 | 2.8 | 7.4 | 176.0 | 147 | 62 | 58 | 4 | 55 | 144 | 10 | 0 | 0 | 1 | 17 | 2 | 3 | 2.63 |
| SP | McLain, D.McLain, Denny † >> | 24 | 1968 | R | 97 | 24 | 24 | 12 | 6 | 2.68 | .257 | 1.03 | 7.0 | 2.3 | 5.5 | 177.2 | 137 | 54 | 53 | 10 | 46 | 109 | 4 | 0 | 0 | 1 | 16 | 1 | 4 | 3.30 |
| SP | Lincecum, T.Lincecum, Tim >> | 27 | 2011 | R | 50 | 23 | 23 | 6 | 12 | 5.07 | .327 | 1.42 | 8.1 | 4.6 | 6.3 | 126.0 | 114 | 74 | 71 | 6 | 65 | 88 | 1 | 0 | 0 | 1 | 11 | 5 | 4 | 3.89 |
| RP | Doolittle, S.Doolittle, Sean >> | 29 | 2016 | L | 64 | 32 | 0 | 3 | 0 | 2.81 | .294 | 1.22 | 9.0 | 2.2 | 9.9 | 41.2 | 41 | 13 | 13 | 2 | 10 | 45 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 2.24 |
| RP | Williamson, S.Williamson, Scott >> | 27 | 2003 | R | 27 | 23 | 0 | 4 | 0 | 2.30 | .261 | 1.06 | 7.7 | 2.0 | 8.0 | 27.1 | 23 | 7 | 7 | 1 | 6 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.37 |
| CL | Franco, J.Franco, John >> | 28 | 1988 | L | 73 | 52 | 0 | 1 | 9 | 4.65 | .326 | 1.45 | 9.4 | 3.8 | 3.1 | 50.1 | 52 | 26 | 26 | 2 | 21 | 17 | 0 | 26 | 8 | 0 | 0 | 0 | 0 | 4.10 |