| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 96 | 24 | 24 | 7 | 10 | 3.50 | .294 | 1.22 | 7.9 | 3.1 | 4.6 | 175.0 | 153 | 81 | 68 | 9 | 61 | 89 | 5 | 0 | 0 | 0 | 16 | 5 | 4 | 3.78 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 85 | 24 | 24 | 6 | 13 | 6.26 | .332 | 1.48 | 9.1 | 4.1 | 5.7 | 128.0 | 130 | 89 | 89 | 12 | 59 | 81 | 1 | 0 | 0 | 0 | 8 | 2 | 0 | 4.38 |
| SP | Zambrano, C.Zambrano, Carlos >> | 25 | 2006 | R | 48 | 23 | 23 | 9 | 9 | 3.49 | .295 | 1.24 | 6.1 | 5.0 | 5.8 | 142.0 | 97 | 59 | 55 | 6 | 79 | 92 | 0 | 0 | 0 | 0 | 14 | 2 | 4 | 3.96 |
| RP | Percival, T.Percival, Troy >> | 30 | 1999 | R | 78 | 59 | 0 | 3 | 2 | 2.40 | .269 | 1.08 | 6.5 | 3.2 | 7.6 | 75.0 | 54 | 23 | 20 | 3 | 27 | 63 | 0 | 1 | 3 | 0 | 0 | 2 | 2 | 3.00 |
| RP | Thigpen, B.Thigpen, Bobby >> | 27 | 1990 | R | 74 | 51 | 0 | 3 | 2 | 2.97 | .248 | 0.99 | 5.7 | 3.3 | 5.8 | 57.2 | 36 | 19 | 19 | 2 | 21 | 37 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.26 |
| RP | Hough, C.Hough, Charlie >> | 26 | 1974 | R | 68 | 35 | 0 | 2 | 4 | 4.60 | .341 | 1.49 | 8.6 | 4.8 | 5.6 | 47.0 | 45 | 29 | 24 | 3 | 25 | 29 | 0 | 2 | 2 | 0 | 0 | 3 | 6 | 4.38 |
| RP | Jansen, K.Jansen, Kenley >> | 26 | 2014 | R | 59 | 19 | 0 | 1 | 0 | 0.90 | .250 | 0.90 | 7.2 | 0.9 | 8.1 | 20.0 | 16 | 3 | 2 | 1 | 2 | 18 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 2.45 |
| CL | Holland, G.Holland, Greg † >> | 28 | 2014 | R | 93 | 45 | 0 | 2 | 3 | 1.65 | .258 | 0.98 | 5.9 | 2.9 | 9.4 | 49.0 | 32 | 10 | 9 | 2 | 16 | 51 | 0 | 27 | 2 | 0 | 0 | 3 | 4 | 2.61 |
| RP | Rosenthal, T.Rosenthal, Trevor >> | 26 | 2016 | R | 9 | 17 | 0 | 1 | 1 | 3.96 | .375 | 1.80 | 9.7 | 6.5 | 7.9 | 25.0 | 27 | 12 | 11 | 1 | 18 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.92 |
| SP | Blyleven, B.Blyleven, Bert >> | 23 | 1974 | R | 56 | 12 | 0 | 0 | 0 | 2.98 | .289 | 1.17 | 7.7 | 2.8 | 4.1 | 57.1 | 49 | 20 | 19 | 2 | 18 | 26 | 0 | 1 | 0 | 0 | 0 | 3 | 2 | 3.65 |