| SP | Militello, S.Militello, Sam >> | 38 | 1992 | R | 84 | 36 | 36 | 12 | 14 | 3.63 | .303 | 1.27 | 8.6 | 2.8 | 6.3 | 238.0 | 228 | 100 | 96 | 29 | 75 | 167 | 0 | 0 | 0 | 0 | 23 | 8 | 3 | 4.23 |
| SP | Pettitte, A.Pettitte, Andy # >> | 35 | 2005 | L | 77 | 36 | 36 | 14 | 14 | 5.20 | .333 | 1.48 | 10.7 | 2.6 | 6.6 | 225.0 | 268 | 139 | 130 | 37 | 64 | 165 | 2 | 0 | 0 | 0 | 17 | 5 | 2 | 4.59 |
| SP | Karstens, J.Karstens, Jeff >> | 25 | 2006 | R | 71 | 35 | 35 | 7 | 17 | 6.99 | .340 | 1.52 | 10.7 | 3.0 | 6.3 | 175.0 | 208 | 141 | 136 | 28 | 58 | 122 | 0 | 0 | 0 | 0 | 7 | 4 | 14 | 4.75 |
| SP | Wang, C.Wang, Chien-Ming # >> | 27 | 2005 | R | 66 | 32 | 32 | 11 | 14 | 5.60 | .340 | 1.49 | 10.5 | 2.9 | 5.3 | 199.1 | 233 | 130 | 124 | 27 | 64 | 117 | 4 | 0 | 0 | 0 | 13 | 11 | 2 | 4.72 |
| SP | Foppert, J.Foppert, Jesse >> | 27 | 2003 | R | 65 | 23 | 22 | 8 | 6 | 4.13 | .326 | 1.44 | 8.7 | 4.4 | 6.5 | 104.2 | 100 | 51 | 48 | 16 | 51 | 75 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 5.06 |
| RP | Choate, R.Choate, Randy >> | 32 | 2001 | L | 88 | 100 | 0 | 5 | 0 | 1.93 | .246 | 0.95 | 5.7 | 2.9 | 5.6 | 74.2 | 47 | 17 | 16 | 2 | 24 | 46 | 0 | 3 | 0 | 0 | 0 | 2 | 3 | 3.16 |
| RP | Glover, G.Glover, Gary >> | 31 | 2001 | R | 58 | 104 | 0 | 6 | 8 | 3.82 | .291 | 1.20 | 9.6 | 1.3 | 6.2 | 96.2 | 102 | 44 | 41 | 4 | 14 | 66 | 0 | 5 | 3 | 0 | 0 | 3 | 4 | 2.70 |
| RP | MacDougal, M.MacDougal, Mike >> | 30 | 2003 | R | 55 | 65 | 0 | 2 | 5 | 3.48 | .301 | 1.26 | 8.9 | 2.5 | 6.2 | 62.0 | 61 | 26 | 24 | 7 | 17 | 43 | 0 | 9 | 1 | 0 | 0 | 2 | 3 | 4.00 |
| RP | Rivera, M.Rivera, Mariano >> | 38 | 2006 | R | 52 | 49 | 0 | 2 | 0 | 1.18 | .217 | 0.79 | 5.8 | 1.4 | 6.2 | 45.2 | 29 | 8 | 6 | 2 | 7 | 31 | 0 | 11 | 1 | 0 | 0 | 2 | 0 | 2.80 |
| RP | Grabow, J.Grabow, John >> | 29 | 2005 | L | 51 | 74 | 0 | 2 | 0 | 3.25 | .269 | 1.06 | 7.8 | 1.9 | 9.0 | 52.2 | 45 | 19 | 19 | 6 | 11 | 52 | 0 | 10 | 1 | 0 | 0 | 2 | 2 | 3.25 |
| RP | Cabrera, F.Cabrera, Fernando >> | 26 | 2006 | R | 51 | 35 | 0 | 3 | 1 | 2.41 | .301 | 1.24 | 7.2 | 4.0 | 8.1 | 41.0 | 33 | 11 | 11 | 2 | 18 | 37 | 0 | 3 | 3 | 0 | 0 | 2 | 3 | 3.29 |
| SP | Rodriguez, R.Rodriguez, Ricardo >> | 29 | 2002 | R | 66 | 37 | 1 | 8 | 3 | 4.35 | .309 | 1.33 | 9.5 | 2.5 | 5.8 | 134.1 | 141 | 72 | 65 | 15 | 37 | 87 | 1 | 0 | 1 | 0 | 1 | 2 | 4 | 4.03 |