| SP | Buehrle, M.Buehrle, Mark >> | 28 | 2001 | L | 92 | 39 | 39 | 25 | 8 | 2.79 | .273 | 1.11 | 8.4 | 1.6 | 6.2 | 319.1 | 297 | 109 | 99 | 22 | 57 | 221 | 23 | 0 | 0 | 2 | 29 | 6 | 5 | 3.10 |
| SP | Maddux, G.Maddux, Greg >> | 41 | 1995 | R | 73 | 29 | 29 | 10 | 8 | 4.69 | .341 | 1.51 | 9.5 | 4.0 | 5.8 | 165.0 | 175 | 97 | 86 | 13 | 74 | 107 | 1 | 0 | 0 | 0 | 15 | 7 | 2 | 4.20 |
| RP | Barcelo, L.Barcelo, Lorenzo >> | 30 | 2000 | R | 90 | 85 | 0 | 6 | 5 | 2.56 | .270 | 1.08 | 6.8 | 2.9 | 6.1 | 144.0 | 108 | 47 | 41 | 6 | 47 | 97 | 0 | 17 | 4 | 0 | 0 | 5 | 3 | 3.28 |
| RP | Ginter, M.Ginter, Matt >> | 30 | 2001 | R | 84 | 55 | 0 | 10 | 9 | 3.61 | .284 | 1.16 | 7.4 | 3.0 | 6.8 | 92.1 | 76 | 43 | 37 | 9 | 31 | 70 | 0 | 9 | 3 | 0 | 0 | 3 | 5 | 3.86 |
| RP | Beltran, F.Beltran, Francis >> | 28 | 2004 | R | 83 | 25 | 0 | 1 | 7 | 4.97 | .339 | 1.50 | 11.5 | 2.2 | 7.6 | 25.1 | 32 | 14 | 14 | 6 | 6 | 21 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 5.28 |
| RP | Castillo, C.Castillo, Carlos >> | 32 | 1997 | R | 76 | 1 | 0 | 0 | 0 | 0.00 | .250 | 1.00 | 4.5 | 4.5 | 18.0 | 2.0 | 1 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.50 |