| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 29 | 29 | 17 | 5 | 3.67 | .291 | 1.21 | 8.0 | 2.9 | 5.0 | 179.0 | 160 | 75 | 73 | 18 | 57 | 99 | 0 | 0 | 0 | 0 | 20 | 3 | 5 | 4.21 |
| SP | Richard, J.Richard, J.R. # >> | 30 | 1980 | R | 90 | 28 | 28 | 8 | 8 | 3.78 | .293 | 1.23 | 7.1 | 3.9 | 8.1 | 162.0 | 128 | 71 | 68 | 12 | 71 | 145 | 0 | 0 | 0 | 0 | 16 | 2 | 2 | 3.52 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 28 | 28 | 11 | 11 | 3.75 | .315 | 1.34 | 8.0 | 4.1 | 4.5 | 182.1 | 162 | 84 | 76 | 16 | 83 | 91 | 1 | 0 | 0 | 0 | 17 | 6 | 3 | 4.61 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 27 | 27 | 12 | 7 | 3.67 | .298 | 1.24 | 7.5 | 3.6 | 7.0 | 174.0 | 145 | 72 | 71 | 13 | 70 | 136 | 4 | 0 | 0 | 1 | 18 | 7 | 4 | 3.74 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 27 | 27 | 10 | 10 | 5.08 | .316 | 1.35 | 8.6 | 3.5 | 5.7 | 168.1 | 161 | 101 | 95 | 20 | 66 | 107 | 6 | 0 | 0 | 1 | 12 | 6 | 7 | 4.56 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 96 | 0 | 2 | 4 | 3.09 | .318 | 1.37 | 6.6 | 5.9 | 9.2 | 78.2 | 57 | 28 | 27 | 6 | 51 | 80 | 0 | 8 | 1 | 0 | 0 | 2 | 0 | 3.99 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 76 | 0 | 3 | 3 | 2.55 | .287 | 1.15 | 6.2 | 4.2 | 9.9 | 67.0 | 46 | 21 | 19 | 10 | 31 | 74 | 0 | 8 | 3 | 0 | 0 | 4 | 4 | 4.30 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 33 | 19 | 0 | 1 | 1 | 5.93 | .379 | 1.83 | 10.4 | 6.9 | 5.5 | 13.2 | 15 | 9 | 9 | 1 | 10 | 8 | 0 | 5 | 2 | 0 | 0 | 0 | 1 | 5.08 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 37 | 14 | 0 | 0 | 2 | 3.18 | .261 | 1.06 | 5.8 | 3.7 | 4.8 | 17.0 | 11 | 6 | 6 | 0 | 7 | 9 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.18 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 41 | 10 | 0 | 3 | 1 | 2.10 | .252 | 0.97 | 5.0 | 4.0 | 7.6 | 25.2 | 14 | 6 | 6 | 1 | 11 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.28 |