| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 81 | 29 | 28 | 16 | 5 | 2.86 | .278 | 1.14 | 6.9 | 3.4 | 8.0 | 182.1 | 139 | 61 | 58 | 18 | 68 | 161 | 0 | 0 | 0 | 0 | 19 | 4 | 11 | 3.70 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 28 | 27 | 11 | 13 | 4.90 | .325 | 1.42 | 9.6 | 3.2 | 5.8 | 192.2 | 205 | 111 | 105 | 27 | 68 | 124 | 7 | 1 | 0 | 1 | 12 | 5 | 4 | 4.68 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 27 | 27 | 13 | 9 | 4.22 | .294 | 1.22 | 7.8 | 3.2 | 7.4 | 168.2 | 145 | 82 | 79 | 19 | 60 | 139 | 0 | 0 | 0 | 0 | 15 | 6 | 4 | 3.99 |
| SP | Lundgren, C.Lundgren, Carl † >> | 27 | 1907 | R | 43 | 28 | 27 | 14 | 8 | 3.69 | .291 | 1.21 | 6.3 | 4.6 | 3.9 | 202.1 | 141 | 87 | 83 | 19 | 103 | 87 | 5 | 0 | 0 | 1 | 17 | 5 | 6 | 4.97 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 59 | 0 | 2 | 9 | 4.21 | .314 | 1.34 | 6.1 | 6.0 | 10.0 | 62.0 | 42 | 30 | 29 | 6 | 41 | 69 | 0 | 33 | 6 | 0 | 0 | 2 | 1 | 4.11 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 71 | 0 | 1 | 2 | 3.42 | .321 | 1.38 | 8.1 | 4.3 | 5.7 | 79.0 | 71 | 32 | 30 | 11 | 38 | 50 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 5.10 |
| RP | Clippard, T.Clippard, Tyler # >> | 26 | 2011 | R | 79 | 62 | 0 | 1 | 4 | 4.09 | .296 | 1.20 | 8.1 | 2.9 | 8.6 | 50.2 | 45 | 24 | 23 | 11 | 16 | 48 | 0 | 2 | 4 | 0 | 0 | 3 | 1 | 5.08 |
| RP | Holland, A.Holland, Al >> | 31 | 1983 | L | 33 | 51 | 0 | 3 | 3 | 2.27 | .281 | 1.13 | 5.4 | 5.0 | 7.3 | 47.2 | 28 | 15 | 12 | 2 | 26 | 38 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 3.72 |