| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 5 | 5 | 3 | 2 | 3.38 | .281 | 1.18 | 9.0 | 1.6 | 5.4 | 40.0 | 40 | 16 | 15 | 8 | 7 | 24 | 2 | 0 | 0 | 0 | 4 | 0 | 0 | 4.93 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 5 | 5 | 1 | 1 | 6.25 | .326 | 1.42 | 10.7 | 2.3 | 7.3 | 31.2 | 37 | 22 | 22 | 9 | 8 | 25 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 6.03 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 4 | 4 | 0 | 0 | 4.13 | .314 | 1.38 | 7.9 | 4.5 | 7.5 | 24.0 | 21 | 12 | 11 | 2 | 12 | 20 | 0 | 0 | 0 | 0 | 3 | 0 | 2 | 3.92 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 11 | 0 | 1 | 2 | 2.03 | .167 | 0.60 | 2.8 | 2.8 | 9.0 | 13.1 | 4 | 4 | 3 | 1 | 4 | 13 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.92 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 11 | 0 | 3 | 0 | 5.14 | .344 | 1.50 | 10.9 | 2.6 | 9.0 | 14.0 | 17 | 8 | 8 | 2 | 4 | 14 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 3.93 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 8 | 0 | 1 | 0 | 0.00 | .256 | 0.93 | 3.0 | 6.0 | 7.0 | 9.2 | 3 | 0 | 0 | 0 | 6 | 7 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.78 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 9 | 0 | 2 | 2 | 1.54 | .255 | 1.03 | 6.5 | 3.3 | 6.5 | 11.2 | 8 | 3 | 2 | 0 | 4 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.64 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 7 | 0 | 0 | 0 | 3.52 | .343 | 1.57 | 7.7 | 7.7 | 7.7 | 7.2 | 6 | 3 | 3 | 0 | 6 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.86 |