| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 14 | 14 | 4 | 5 | 3.71 | .288 | 1.20 | 8.3 | 2.6 | 9.9 | 87.1 | 80 | 36 | 36 | 8 | 25 | 96 | 0 | 0 | 0 | 0 | 9 | 1 | 0 | 2.89 |
| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 14 | 14 | 4 | 5 | 5.15 | .324 | 1.39 | 9.4 | 3.2 | 8.7 | 85.2 | 89 | 50 | 49 | 11 | 30 | 82 | 0 | 0 | 0 | 0 | 7 | 4 | 1 | 3.95 |
| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 14 | 14 | 7 | 6 | 4.28 | .327 | 1.42 | 9.5 | 3.4 | 6.9 | 96.2 | 101 | 46 | 46 | 9 | 36 | 74 | 2 | 0 | 0 | 1 | 6 | 4 | 2 | 3.93 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 16 | 14 | 3 | 9 | 5.97 | .365 | 1.71 | 11.3 | 4.1 | 5.2 | 98.0 | 123 | 70 | 65 | 14 | 45 | 57 | 1 | 0 | 0 | 0 | 4 | 1 | 2 | 5.10 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 35 | 0 | 2 | 1 | 2.58 | .292 | 1.19 | 6.4 | 4.4 | 9.0 | 45.1 | 32 | 18 | 13 | 7 | 22 | 45 | 0 | 4 | 0 | 0 | 0 | 2 | 0 | 4.62 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 22 | 0 | 2 | 1 | 3.58 | .265 | 1.08 | 7.3 | 2.7 | 9.3 | 27.2 | 22 | 11 | 11 | 5 | 8 | 28 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.22 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 16 | 0 | 1 | 1 | 3.98 | .358 | 1.67 | 11.3 | 4.1 | 8.1 | 20.1 | 25 | 9 | 9 | 5 | 9 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.80 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 7 | 0 | 0 | 4 | 3.06 | .293 | 1.25 | 8.5 | 3.2 | 8.5 | 17.2 | 16 | 11 | 6 | 2 | 6 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.71 |