| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 34 | 34 | 17 | 10 | 2.93 | .281 | 1.14 | 7.2 | 3.1 | 7.5 | 260.2 | 208 | 89 | 85 | 26 | 90 | 218 | 5 | 0 | 0 | 2 | 24 | 7 | 0 | 3.74 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 32 | 32 | 10 | 10 | 5.00 | .336 | 1.51 | 9.9 | 3.7 | 7.4 | 209.0 | 229 | 120 | 116 | 35 | 86 | 172 | 4 | 0 | 0 | 0 | 14 | 2 | 7 | 4.79 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 32 | 32 | 17 | 7 | 3.77 | .287 | 1.19 | 9.2 | 1.6 | 4.4 | 233.2 | 237 | 104 | 98 | 27 | 42 | 113 | 4 | 0 | 0 | 1 | 19 | 3 | 0 | 4.12 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 32 | 31 | 12 | 10 | 4.21 | .313 | 1.34 | 8.5 | 3.6 | 5.4 | 214.0 | 202 | 108 | 100 | 25 | 85 | 128 | 2 | 0 | 0 | 0 | 19 | 6 | 2 | 4.60 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 97 | 0 | 3 | 4 | 3.66 | .287 | 1.19 | 8.2 | 2.6 | 7.0 | 66.1 | 60 | 29 | 27 | 7 | 19 | 51 | 0 | 8 | 5 | 0 | 0 | 1 | 4 | 3.74 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 63 | 0 | 6 | 7 | 4.09 | .312 | 1.30 | 9.5 | 2.3 | 8.3 | 50.2 | 53 | 26 | 23 | 9 | 13 | 46 | 0 | 11 | 4 | 0 | 0 | 3 | 2 | 4.46 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 32 | 0 | 5 | 4 | 3.18 | .346 | 1.52 | 9.3 | 4.5 | 5.1 | 28.1 | 29 | 12 | 10 | 4 | 14 | 16 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 5.43 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 24 | 0 | 3 | 1 | 3.24 | .306 | 1.32 | 7.6 | 4.3 | 8.6 | 25.0 | 21 | 9 | 9 | 3 | 12 | 24 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.08 |