| SP | Mussina, M.Mussina, Mike >> | 24 | 1992 | R | 85 | 33 | 33 | 12 | 15 | 4.35 | .299 | 1.24 | 8.2 | 3.0 | 5.1 | 217.1 | 197 | 105 | 105 | 34 | 73 | 122 | 10 | 0 | 0 | 3 | 14 | 8 | 3 | 5.03 |
| SP | Buehler, W.Buehler, Walker # >> | 23 | 2021 | R | 75 | 32 | 32 | 12 | 8 | 4.18 | .292 | 1.22 | 7.9 | 3.2 | 8.8 | 165.2 | 144 | 77 | 77 | 24 | 58 | 161 | 0 | 0 | 0 | 0 | 13 | 3 | 1 | 4.05 |
| SP | Fidrych, M.Fidrych, Mark # >> | 32 | 1976 | R | 59 | 31 | 31 | 9 | 13 | 4.98 | .303 | 1.28 | 9.2 | 2.4 | 4.2 | 195.1 | 199 | 115 | 108 | 28 | 51 | 92 | 6 | 0 | 0 | 1 | 9 | 5 | 3 | 4.78 |
| SP | Lincecum, T.Lincecum, Tim >> | 34 | 2008 | R | 50 | 31 | 31 | 11 | 11 | 5.23 | .319 | 1.38 | 8.8 | 3.7 | 8.4 | 156.2 | 152 | 101 | 91 | 26 | 64 | 145 | 0 | 0 | 0 | 0 | 15 | 4 | 7 | 4.62 |
| SP | Niekro, P.Niekro, Phil >> | 32 | 1978 | R | 42 | 30 | 29 | 10 | 12 | 5.97 | .336 | 1.49 | 10.1 | 3.4 | 5.9 | 159.2 | 178 | 114 | 106 | 35 | 60 | 105 | 5 | 0 | 0 | 0 | 11 | 4 | 0 | 5.75 |
| RP | Rodney, F.Rodney, Fernando >> | 28 | 2012 | R | 98 | 87 | 0 | 7 | 3 | 2.37 | .250 | 0.97 | 5.9 | 2.9 | 7.5 | 136.2 | 89 | 37 | 36 | 5 | 44 | 114 | 0 | 10 | 2 | 0 | 0 | 4 | 5 | 2.86 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2012 | L | 74 | 66 | 0 | 5 | 3 | 3.81 | .318 | 1.35 | 7.7 | 4.6 | 9.6 | 75.2 | 64 | 32 | 32 | 6 | 38 | 80 | 0 | 6 | 4 | 0 | 0 | 4 | 4 | 3.59 |
| RP | Soria, J.Soria, Joakim >> | 28 | 2010 | R | 65 | 37 | 0 | 2 | 5 | 5.07 | .360 | 1.67 | 11.0 | 4.2 | 7.4 | 60.1 | 73 | 34 | 34 | 10 | 28 | 49 | 0 | 3 | 2 | 0 | 0 | 1 | 3 | 4.98 |