| SP | Dierker, L.Dierker, Larry # >> | 29 | 1969 | R | 54 | 33 | 33 | 14 | 15 | 5.09 | .308 | 1.30 | 8.7 | 3.0 | 5.5 | 198.0 | 192 | 115 | 112 | 37 | 66 | 121 | 2 | 0 | 0 | 1 | 14 | 7 | 5 | 5.31 |
| SP | Newhouser, H.Newhouser, Hal >> | 22 | 1945 | L | 21 | 32 | 32 | 11 | 15 | 5.39 | .337 | 1.50 | 8.8 | 4.7 | 5.8 | 177.0 | 173 | 109 | 106 | 31 | 92 | 114 | 2 | 0 | 0 | 1 | 13 | 5 | 2 | 5.63 |
| SP | Martinez, P.Martinez, Pedro >> | 31 | 2000 | R | 100 | 32 | 32 | 15 | 10 | 2.79 | .241 | 0.95 | 6.9 | 1.6 | 8.8 | 248.1 | 191 | 85 | 77 | 26 | 45 | 242 | 11 | 0 | 0 | 2 | 24 | 1 | 4 | 2.97 |
| SP | Sanchez, C.Sanchez, Cristopher # >> | 22 | 2025 | L | 23 | 31 | 30 | 6 | 10 | 5.53 | .308 | 1.32 | 9.1 | 2.8 | 7.9 | 167.2 | 169 | 106 | 103 | 29 | 52 | 147 | 0 | 1 | 0 | 0 | 12 | 3 | 4 | 4.49 |
| SP | Bunning, J.Bunning, Jim >> | 36 | 1966 | R | 22 | 29 | 29 | 6 | 13 | 5.52 | .328 | 1.42 | 10.1 | 2.7 | 5.4 | 164.2 | 184 | 114 | 101 | 41 | 50 | 98 | 6 | 0 | 0 | 1 | 11 | 7 | 2 | 6.10 |
| RP | Jansen, K.Jansen, Kenley >> | 37 | 2017 | R | 14 | 79 | 0 | 4 | 4 | 4.35 | .275 | 1.12 | 7.7 | 2.4 | 9.8 | 97.1 | 83 | 47 | 47 | 18 | 26 | 106 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 4.09 |
| RP | McGraw, T.McGraw, Tug # >> | 37 | 1971 | L | 26 | 84 | 0 | 3 | 3 | 4.20 | .291 | 1.22 | 8.6 | 2.4 | 6.5 | 105.0 | 100 | 51 | 49 | 17 | 28 | 76 | 0 | 1 | 1 | 0 | 0 | 1 | 5 | 4.49 |
| RP | Jackson, M.Jackson, Mike >> | 31 | 1998 | R | 77 | 68 | 0 | 6 | 5 | 3.84 | .268 | 1.09 | 7.6 | 2.2 | 5.0 | 89.0 | 75 | 41 | 38 | 13 | 22 | 49 | 0 | 0 | 3 | 0 | 0 | 1 | 2 | 4.57 |
| SU | Hiller, J.Hiller, John >> | 37 | 1973 | L | 63 | 73 | 0 | 2 | 4 | 3.97 | .282 | 1.14 | 8.1 | 2.2 | 6.7 | 90.2 | 81 | 44 | 40 | 9 | 22 | 67 | 0 | 8 | 3 | 0 | 0 | 4 | 4 | 3.68 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 30 | 2006 | R | 68 | 67 | 0 | 3 | 7 | 3.30 | .299 | 1.27 | 8.0 | 3.4 | 8.4 | 71.0 | 63 | 30 | 26 | 6 | 27 | 66 | 0 | 34 | 8 | 0 | 0 | 1 | 0 | 3.42 |