| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 13 | 13 | 1 | 6 | 3.76 | .287 | 1.20 | 7.5 | 3.3 | 10.2 | 91.0 | 76 | 38 | 38 | 15 | 33 | 103 | 2 | 0 | 0 | 1 | 7 | 1 | 2 | 4.00 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 13 | 13 | 4 | 5 | 5.91 | .341 | 1.51 | 9.9 | 3.6 | 8.7 | 67.0 | 74 | 44 | 44 | 12 | 27 | 65 | 0 | 0 | 0 | 0 | 5 | 3 | 4 | 4.73 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 78 | 12 | 12 | 6 | 3 | 4.52 | .290 | 1.22 | 8.4 | 2.7 | 6.3 | 77.2 | 72 | 41 | 39 | 12 | 23 | 54 | 3 | 0 | 0 | 0 | 7 | 0 | 1 | 4.52 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 74 | 12 | 12 | 3 | 4 | 6.92 | .347 | 1.60 | 10.2 | 4.2 | 6.8 | 52.0 | 59 | 40 | 40 | 8 | 24 | 39 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 4.88 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 13 | 12 | 4 | 3 | 5.11 | .317 | 1.36 | 9.4 | 2.9 | 9.7 | 74.0 | 77 | 43 | 42 | 6 | 24 | 80 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 2.95 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 35 | 0 | 2 | 0 | 2.63 | .258 | 1.00 | 6.4 | 2.6 | 9.8 | 48.0 | 34 | 14 | 14 | 5 | 14 | 52 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 3.19 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 75 | 25 | 0 | 2 | 4 | 4.50 | .354 | 1.64 | 10.0 | 4.8 | 8.0 | 28.0 | 31 | 14 | 14 | 3 | 15 | 25 | 0 | 0 | 3 | 0 | 0 | 0 | 1 | 4.21 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 64 | 15 | 0 | 1 | 1 | 1.86 | .247 | 0.98 | 6.6 | 2.4 | 9.5 | 19.1 | 14 | 4 | 4 | 1 | 5 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.37 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 94 | 29 | 0 | 3 | 1 | 1.36 | .233 | 0.91 | 4.1 | 4.1 | 9.8 | 33.0 | 15 | 5 | 5 | 1 | 15 | 36 | 0 | 16 | 2 | 0 | 0 | 0 | 0 | 2.58 |