| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 34 | 34 | 12 | 12 | 3.48 | .262 | 1.04 | 7.9 | 1.5 | 8.3 | 237.2 | 209 | 98 | 92 | 27 | 39 | 219 | 6 | 0 | 0 | 2 | 22 | 5 | 6 | 3.19 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 96 | 34 | 34 | 13 | 13 | 3.82 | .284 | 1.17 | 7.6 | 3.0 | 8.2 | 216.2 | 182 | 96 | 92 | 22 | 72 | 197 | 4 | 0 | 0 | 1 | 18 | 4 | 0 | 3.56 |
| SP | McNally, D.McNally, Dave # >> | 26 | 1968 | L | 95 | 34 | 34 | 8 | 16 | 4.78 | .306 | 1.30 | 9.0 | 2.7 | 5.6 | 194.0 | 193 | 107 | 103 | 28 | 59 | 120 | 3 | 0 | 0 | 0 | 14 | 5 | 4 | 4.63 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 84 | 33 | 33 | 14 | 10 | 3.59 | .271 | 1.09 | 7.8 | 2.1 | 4.9 | 215.2 | 186 | 92 | 86 | 17 | 50 | 117 | 4 | 0 | 0 | 2 | 17 | 4 | 4 | 3.69 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 26 | 25 | 7 | 9 | 4.38 | .304 | 1.28 | 8.3 | 3.3 | 5.9 | 152.0 | 140 | 80 | 74 | 21 | 55 | 100 | 2 | 0 | 0 | 0 | 12 | 4 | 3 | 4.64 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 84 | 0 | 2 | 5 | 3.29 | .307 | 1.32 | 7.6 | 4.3 | 10.1 | 90.1 | 76 | 37 | 33 | 6 | 43 | 101 | 0 | 3 | 3 | 0 | 0 | 1 | 6 | 3.09 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 59 | 0 | 4 | 3 | 2.05 | .303 | 1.29 | 7.0 | 4.6 | 8.6 | 66.0 | 51 | 15 | 15 | 4 | 34 | 63 | 0 | 1 | 6 | 0 | 0 | 1 | 2 | 3.47 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 28 | 0 | 3 | 1 | 1.71 | .258 | 1.01 | 5.5 | 3.8 | 5.8 | 31.2 | 19 | 6 | 6 | 2 | 13 | 20 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.90 |
| RP | Marmol, C.Marmol, Carlos >> | 28 | 2010 | R | 43 | 27 | 0 | 0 | 2 | 4.55 | .336 | 1.52 | 8.1 | 5.9 | 11.5 | 29.2 | 26 | 15 | 15 | 3 | 19 | 37 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.76 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 32 | 0 | 4 | 1 | 3.93 | .312 | 1.34 | 7.4 | 4.7 | 6.0 | 94.0 | 77 | 45 | 41 | 6 | 49 | 63 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 4.12 |
| CL | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 69 | 0 | 8 | 8 | 3.67 | .278 | 1.15 | 8.3 | 2.2 | 6.9 | 73.2 | 67 | 30 | 30 | 9 | 18 | 56 | 0 | 38 | 3 | 0 | 0 | 0 | 0 | 3.81 |