| SP | Peralta, F.Peralta, Freddy >> | 25 | 2021 | R | 85 | 21 | 21 | 3 | 4 | 3.13 | .284 | 1.14 | 6.2 | 4.1 | 9.0 | 83.1 | 57 | 29 | 29 | 10 | 38 | 83 | 0 | 0 | 0 | 0 | 1 | 4 | 1 | 4.08 |
| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 39 | 20 | 19 | 4 | 5 | 4.86 | .306 | 1.32 | 8.6 | 3.4 | 9.2 | 83.1 | 79 | 45 | 45 | 17 | 31 | 85 | 0 | 1 | 0 | 0 | 7 | 0 | 2 | 4.73 |
| SP | Strider, S.Strider, Spencer >> | 23 | 2022 | R | 72 | 20 | 20 | 0 | 1 | 4.71 | .311 | 1.34 | 7.3 | 4.7 | 10.5 | 65.0 | 53 | 36 | 34 | 11 | 34 | 76 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.48 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 80 | 55 | 0 | 3 | 0 | 2.61 | .263 | 1.04 | 5.5 | 3.9 | 6.7 | 69.0 | 42 | 20 | 20 | 9 | 30 | 51 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 4.61 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 43 | 0 | 2 | 5 | 2.21 | .318 | 1.40 | 8.3 | 4.5 | 11.0 | 40.2 | 37 | 12 | 10 | 5 | 20 | 49 | 0 | 6 | 2 | 0 | 0 | 0 | 0 | 3.68 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 59 | 31 | 0 | 4 | 2 | 1.60 | .241 | 0.89 | 5.2 | 3.0 | 10.1 | 33.2 | 19 | 7 | 6 | 3 | 11 | 37 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 3.12 |
| RP | Estevez, C.Estevez, Carlos >> | 31 | 2024 | R | 49 | 19 | 0 | 4 | 0 | 0.90 | .221 | 0.85 | 5.9 | 1.8 | 8.6 | 20.0 | 13 | 3 | 2 | 0 | 4 | 19 | 0 | 3 | 3 | 0 | 0 | 0 | 1 | 1.70 |
| RP | Okajima, H.Okajima, Hideki >> | 32 | 2007 | L | 29 | 54 | 0 | 0 | 1 | 3.30 | .276 | 1.10 | 7.2 | 2.7 | 7.6 | 46.1 | 37 | 19 | 17 | 3 | 14 | 39 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 3.20 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 69 | 0 | 13 | 0 | 2.63 | .261 | 1.06 | 6.0 | 3.7 | 11.7 | 27.1 | 18 | 8 | 8 | 4 | 11 | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.56 |