| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 35 | 35 | 18 | 10 | 3.09 | .250 | 0.97 | 6.7 | 2.0 | 10.1 | 224.1 | 167 | 83 | 77 | 24 | 51 | 252 | 2 | 0 | 0 | 1 | 27 | 6 | 0 | 2.91 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 35 | 35 | 15 | 14 | 3.51 | .260 | 1.02 | 7.0 | 2.3 | 8.1 | 235.2 | 182 | 95 | 92 | 18 | 59 | 211 | 8 | 0 | 0 | 3 | 25 | 7 | 4 | 3.04 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 35 | 35 | 13 | 14 | 4.87 | .320 | 1.39 | 9.1 | 3.4 | 9.9 | 188.1 | 191 | 104 | 102 | 20 | 71 | 206 | 0 | 0 | 0 | 0 | 19 | 4 | 1 | 3.39 |
| SP | Strider, S.Strider, Spencer >> | 23 | 2022 | R | 71 | 34 | 34 | 4 | 7 | 4.42 | .327 | 1.45 | 8.1 | 5.0 | 7.9 | 144.2 | 130 | 71 | 71 | 8 | 80 | 127 | 0 | 0 | 0 | 0 | 4 | 1 | 3 | 3.65 |
| SP | Johnson, R.Johnson, Randy # >> | 38 | 2001 | L | 53 | 30 | 29 | 12 | 12 | 4.51 | .290 | 1.20 | 8.3 | 2.5 | 8.7 | 183.2 | 169 | 100 | 92 | 30 | 51 | 177 | 3 | 0 | 0 | 2 | 16 | 5 | 7 | 4.11 |
| SU | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 70 | 0 | 2 | 0 | 2.28 | .287 | 1.21 | 6.3 | 4.6 | 10.7 | 67.0 | 47 | 19 | 17 | 4 | 34 | 80 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 2.91 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 66 | 0 | 4 | 6 | 3.23 | .257 | 1.01 | 5.3 | 3.9 | 8.8 | 94.2 | 55 | 35 | 34 | 9 | 41 | 92 | 0 | 17 | 4 | 0 | 0 | 2 | 4 | 3.66 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 99 | 0 | 5 | 4 | 4.16 | .306 | 1.30 | 8.5 | 3.2 | 8.7 | 97.1 | 92 | 49 | 45 | 15 | 35 | 94 | 0 | 17 | 3 | 0 | 0 | 2 | 2 | 4.22 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 55 | 0 | 2 | 3 | 4.15 | .316 | 1.38 | 8.1 | 4.3 | 6.9 | 52.0 | 47 | 29 | 24 | 8 | 25 | 40 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.90 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 39 | 0 | 2 | 0 | 3.65 | .297 | 1.22 | 5.6 | 5.4 | 11.2 | 37.0 | 23 | 16 | 15 | 3 | 22 | 46 | 0 | 1 | 2 | 0 | 0 | 2 | 1 | 3.51 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 42 | 36 | 1 | 9 | 3 | 4.33 | .314 | 1.34 | 7.5 | 4.6 | 7.8 | 112.1 | 93 | 56 | 54 | 11 | 57 | 97 | 0 | 2 | 0 | 0 | 0 | 4 | 6 | 4.18 |