| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 15 | 15 | 7 | 4 | 2.22 | .238 | 0.94 | 6.3 | 2.2 | 8.2 | 117.1 | 82 | 29 | 29 | 11 | 28 | 106 | 4 | 0 | 0 | 3 | 11 | 0 | 1 | 3.13 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 97 | 14 | 14 | 0 | 3 | 3.72 | .273 | 1.13 | 8.3 | 2.0 | 6.5 | 36.1 | 33 | 15 | 15 | 8 | 8 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.11 |
| SP | Gilbert, T.Gilbert, Tyler >> | 27 | 2021 | L | 64 | 15 | 15 | 0 | 5 | 5.22 | .300 | 1.29 | 7.8 | 3.9 | 5.1 | 39.2 | 34 | 23 | 23 | 5 | 17 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.85 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 55 | 15 | 15 | 5 | 4 | 3.33 | .298 | 1.25 | 8.3 | 2.9 | 5.6 | 81.0 | 75 | 31 | 30 | 8 | 26 | 50 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 4.09 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 76 | 44 | 0 | 6 | 0 | 2.25 | .284 | 1.15 | 5.2 | 5.2 | 8.8 | 52.0 | 30 | 13 | 13 | 2 | 30 | 51 | 0 | 3 | 0 | 0 | 0 | 2 | 1 | 3.38 |
| RP | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 72 | 38 | 0 | 2 | 2 | 3.06 | .257 | 1.02 | 5.2 | 4.0 | 5.8 | 50.0 | 29 | 17 | 17 | 5 | 22 | 32 | 0 | 3 | 1 | 0 | 0 | 1 | 3 | 4.40 |
| RP | Kim, B.Kim, Byung-Hyun >> | 22 | 2001 | R | 56 | 35 | 0 | 3 | 1 | 3.29 | .305 | 1.27 | 6.1 | 5.3 | 8.8 | 41.0 | 28 | 16 | 15 | 2 | 24 | 40 | 0 | 5 | 1 | 0 | 0 | 2 | 2 | 3.59 |
| RP | Ginkel, K.Ginkel, Kevin >> | 29 | 2023 | R | 65 | 26 | 0 | 2 | 2 | 3.78 | .296 | 1.26 | 7.4 | 4.1 | 7.1 | 33.1 | 27 | 14 | 14 | 4 | 15 | 26 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 4.36 |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 53 | 22 | 0 | 2 | 0 | 3.62 | .274 | 1.10 | 7.3 | 2.7 | 5.7 | 27.1 | 22 | 11 | 11 | 3 | 8 | 17 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 4.19 |