| SP | Verlander, J.Verlander, Justin # >> | 28 | 2011 | R | 87 | 34 | 34 | 11 | 13 | 4.61 | .305 | 1.28 | 8.6 | 3.0 | 6.9 | 224.1 | 213 | 115 | 115 | 27 | 75 | 172 | 4 | 0 | 0 | 0 | 13 | 7 | 3 | 4.13 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 80 | 33 | 33 | 8 | 13 | 5.42 | .339 | 1.52 | 9.9 | 3.9 | 5.8 | 194.1 | 213 | 123 | 117 | 23 | 83 | 125 | 2 | 0 | 0 | 2 | 12 | 3 | 3 | 4.58 |
| SP | Skubal, T.Skubal, Tarik >> | 27 | 2024 | L | 76 | 33 | 33 | 14 | 7 | 4.89 | .340 | 1.52 | 10.4 | 3.3 | 7.3 | 178.2 | 206 | 102 | 97 | 19 | 66 | 144 | 0 | 0 | 0 | 0 | 18 | 4 | 3 | 3.95 |
| SP | Scherzer, M.Scherzer, Max # >> | 29 | 2013 | R | 73 | 31 | 31 | 11 | 12 | 4.86 | .333 | 1.48 | 9.9 | 3.4 | 8.3 | 181.2 | 200 | 101 | 98 | 26 | 68 | 167 | 2 | 0 | 0 | 1 | 16 | 4 | 6 | 4.22 |
| SP | Aguirre, H.Aguirre, Hank >> | 31 | 1962 | L | 55 | 31 | 31 | 8 | 9 | 5.45 | .341 | 1.50 | 9.3 | 4.2 | 5.7 | 147.0 | 152 | 90 | 89 | 27 | 68 | 93 | 0 | 0 | 0 | 0 | 10 | 8 | 0 | 5.67 |
| CL | Greene, S.Greene, Shane >> | 30 | 2019 | R | 86 | 67 | 0 | 0 | 10 | 4.16 | .327 | 1.42 | 8.7 | 4.1 | 10.1 | 71.1 | 69 | 41 | 33 | 8 | 32 | 80 | 0 | 37 | 9 | 0 | 0 | 3 | 0 | 3.69 |
| RP | Holton, T.Holton, Tyler >> | 28 | 2024 | L | 85 | 85 | 0 | 7 | 5 | 4.62 | .319 | 1.39 | 10.3 | 2.2 | 5.8 | 138.1 | 158 | 71 | 71 | 17 | 34 | 89 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 4.09 |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 74 | 83 | 0 | 6 | 6 | 4.03 | .312 | 1.34 | 7.9 | 4.2 | 9.1 | 98.1 | 86 | 44 | 44 | 12 | 46 | 99 | 0 | 1 | 2 | 0 | 0 | 2 | 6 | 4.04 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 64 | 66 | 0 | 5 | 7 | 5.03 | .326 | 1.43 | 8.8 | 4.1 | 7.6 | 102.0 | 100 | 58 | 57 | 15 | 46 | 86 | 0 | 1 | 4 | 0 | 0 | 2 | 6 | 4.64 |
| RP | Rondon, B.Rondon, Bruce >> | 25 | 2016 | R | 52 | 49 | 0 | 6 | 2 | 5.22 | .320 | 1.40 | 8.7 | 4.0 | 9.5 | 58.2 | 56 | 37 | 34 | 13 | 26 | 61 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 5.21 |
| RP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 47 | 49 | 0 | 1 | 1 | 3.39 | .300 | 1.26 | 8.8 | 2.6 | 6.3 | 82.1 | 80 | 36 | 31 | 7 | 24 | 57 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 3.67 |