| SP | Eovaldi, N.Eovaldi, Nathan >> | 35 | 2025 | R | 89 | 27 | 27 | 12 | 7 | 3.39 | .263 | 1.05 | 7.6 | 1.9 | 6.7 | 183.1 | 154 | 71 | 69 | 27 | 39 | 137 | 1 | 0 | 0 | 0 | 17 | 3 | 3 | 4.11 |
| SP | deGrom, J.deGrom, Jacob # >> | 37 | 2025 | R | 81 | 26 | 26 | 11 | 9 | 4.68 | .312 | 1.35 | 9.2 | 3.0 | 8.6 | 155.2 | 159 | 84 | 81 | 25 | 51 | 148 | 0 | 0 | 0 | 0 | 15 | 2 | 2 | 4.21 |
| SP | Darvish, Y.Darvish, Yu # >> | 26 | 2013 | R | 61 | 25 | 25 | 10 | 6 | 4.96 | .347 | 1.57 | 8.7 | 5.5 | 9.2 | 159.2 | 153 | 91 | 88 | 16 | 97 | 163 | 1 | 0 | 0 | 0 | 11 | 5 | 0 | 4.18 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 96 | 70 | 0 | 7 | 1 | 1.97 | .261 | 1.06 | 5.7 | 3.9 | 9.4 | 118.2 | 75 | 28 | 26 | 6 | 51 | 123 | 0 | 10 | 4 | 0 | 0 | 0 | 0 | 2.87 |
| RP | Uehara, K.Uehara, Koji >> | 37 | 2012 | R | 89 | 62 | 0 | 5 | 4 | 3.94 | .307 | 1.31 | 9.2 | 2.6 | 8.2 | 75.1 | 77 | 35 | 33 | 7 | 22 | 68 | 0 | 7 | 5 | 0 | 0 | 1 | 2 | 3.32 |
| RP | Armstrong, S.Armstrong, Shawn >> | 34 | 2025 | R | 78 | 54 | 0 | 10 | 1 | 2.83 | .268 | 1.08 | 6.3 | 3.5 | 6.5 | 57.1 | 40 | 21 | 18 | 5 | 22 | 41 | 0 | 7 | 3 | 0 | 0 | 1 | 4 | 3.91 |
| RP | Soria, J.Soria, Joakim >> | 30 | 2014 | R | 53 | 17 | 0 | 0 | 1 | 3.60 | .338 | 1.47 | 10.2 | 3.0 | 7.2 | 15.0 | 17 | 6 | 6 | 2 | 5 | 12 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 4.33 |