| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 94 | 34 | 34 | 17 | 12 | 3.71 | .295 | 1.23 | 6.9 | 4.2 | 8.1 | 240.0 | 184 | 102 | 99 | 27 | 112 | 217 | 1 | 0 | 0 | 0 | 21 | 5 | 2 | 4.12 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 84 | 33 | 33 | 16 | 6 | 3.44 | .282 | 1.16 | 6.9 | 3.5 | 8.6 | 214.1 | 165 | 85 | 82 | 27 | 84 | 205 | 0 | 0 | 0 | 0 | 24 | 4 | 2 | 3.96 |
| SP | Harden, R.Harden, Rich † >> | 27 | 2008 | R | 67 | 31 | 31 | 16 | 4 | 3.62 | .292 | 1.22 | 7.5 | 3.5 | 7.7 | 193.2 | 161 | 79 | 78 | 22 | 75 | 166 | 1 | 0 | 0 | 1 | 19 | 4 | 3 | 3.99 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 12 | 1 | 3 | 2 | 3.82 | .293 | 1.21 | 8.5 | 2.5 | 7.8 | 68.1 | 64 | 29 | 29 | 6 | 19 | 59 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.34 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 77 | 0 | 6 | 5 | 2.16 | .292 | 1.22 | 6.5 | 4.5 | 8.9 | 96.0 | 69 | 27 | 23 | 10 | 48 | 95 | 0 | 8 | 5 | 0 | 0 | 2 | 3 | 3.94 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 83 | 0 | 3 | 5 | 3.72 | .267 | 1.05 | 6.2 | 3.2 | 8.2 | 87.0 | 60 | 36 | 36 | 11 | 31 | 79 | 0 | 18 | 8 | 0 | 0 | 4 | 1 | 4.03 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 75 | 56 | 0 | 2 | 7 | 3.12 | .330 | 1.42 | 9.5 | 3.3 | 6.8 | 52.0 | 55 | 21 | 18 | 4 | 19 | 39 | 0 | 8 | 1 | 0 | 0 | 3 | 0 | 3.77 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 72 | 28 | 0 | 2 | 1 | 2.54 | .248 | 0.92 | 5.1 | 3.2 | 8.7 | 28.1 | 16 | 8 | 8 | 4 | 10 | 27 | 0 | 7 | 1 | 0 | 0 | 2 | 0 | 4.21 |
| RP | Benitez, A.Benitez, Armando # >> | 27 | 1999 | R | 57 | 26 | 0 | 1 | 1 | 5.06 | .360 | 1.69 | 9.7 | 5.9 | 12.8 | 26.2 | 28 | 17 | 15 | 1 | 17 | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.62 |
| SP | Darvish, Y.Darvish, Yu # >> | 26 | 2013 | R | 56 | 31 | 31 | 17 | 8 | 3.84 | .294 | 1.23 | 7.4 | 3.6 | 9.2 | 211.0 | 174 | 94 | 90 | 30 | 85 | 216 | 2 | 0 | 0 | 1 | 21 | 5 | 7 | 4.08 |