| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 93 | 29 | 29 | 14 | 8 | 3.62 | .288 | 1.17 | 7.8 | 2.8 | 6.5 | 209.0 | 180 | 85 | 84 | 24 | 65 | 152 | 3 | 0 | 0 | 0 | 16 | 9 | 5 | 4.10 |
| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 90 | 28 | 28 | 15 | 10 | 3.60 | .277 | 1.13 | 7.6 | 2.6 | 6.1 | 202.2 | 171 | 82 | 81 | 24 | 58 | 138 | 7 | 0 | 0 | 0 | 16 | 4 | 2 | 4.10 |
| SP | Seaver, T.Seaver, Tom † >> | 27 | 1971 | R | 81 | 29 | 28 | 14 | 13 | 4.16 | .305 | 1.30 | 8.4 | 3.4 | 8.9 | 196.2 | 182 | 105 | 91 | 32 | 73 | 193 | 6 | 0 | 0 | 1 | 17 | 4 | 3 | 4.33 |
| CL | Davis, W.Davis, Wade † >> | 28 | 2014 | R | 81 | 45 | 0 | 2 | 3 | 2.62 | .276 | 1.14 | 7.4 | 3.1 | 10.2 | 44.2 | 36 | 13 | 13 | 6 | 15 | 50 | 0 | 29 | 3 | 0 | 0 | 0 | 0 | 3.52 |
| SU | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 37 | 0 | 1 | 2 | 2.29 | .213 | 0.81 | 5.8 | 1.6 | 7.4 | 39.1 | 25 | 10 | 10 | 2 | 7 | 32 | 0 | 5 | 4 | 0 | 0 | 0 | 4 | 2.56 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 71 | 51 | 0 | 2 | 4 | 2.48 | .236 | 0.89 | 4.7 | 3.4 | 9.6 | 61.2 | 32 | 17 | 17 | 5 | 23 | 65 | 0 | 1 | 2 | 0 | 0 | 2 | 4 | 3.16 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 64 | 23 | 0 | 1 | 3 | 6.17 | .340 | 1.50 | 7.4 | 6.3 | 7.4 | 23.1 | 19 | 16 | 16 | 6 | 16 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.96 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 12 | 1 | 1 | 1 | 4.34 | .290 | 1.21 | 7.6 | 3.4 | 10.8 | 64.1 | 54 | 31 | 31 | 8 | 24 | 77 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 3.39 |