| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 29 | 29 | 13 | 12 | 2.45 | .254 | 1.01 | 6.8 | 2.3 | 10.1 | 223.2 | 169 | 66 | 61 | 17 | 56 | 250 | 9 | 0 | 0 | 3 | 21 | 3 | 1 | 2.54 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 94 | 28 | 28 | 8 | 10 | 4.24 | .294 | 1.21 | 7.5 | 3.4 | 9.0 | 193.1 | 161 | 91 | 91 | 26 | 73 | 194 | 2 | 0 | 0 | 0 | 15 | 7 | 7 | 3.98 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 28 | 28 | 7 | 11 | 4.83 | .318 | 1.35 | 8.4 | 3.8 | 9.2 | 156.2 | 146 | 86 | 84 | 18 | 65 | 160 | 1 | 0 | 0 | 1 | 14 | 8 | 4 | 3.85 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 72 | 27 | 27 | 5 | 16 | 5.61 | .319 | 1.36 | 8.8 | 3.5 | 6.0 | 171.2 | 167 | 109 | 107 | 32 | 66 | 114 | 5 | 0 | 0 | 0 | 12 | 8 | 2 | 5.40 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 55 | 0 | 1 | 2 | 2.02 | .261 | 1.03 | 6.2 | 3.0 | 9.4 | 62.1 | 43 | 15 | 14 | 5 | 21 | 65 | 0 | 36 | 2 | 0 | 0 | 2 | 4 | 3.06 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 64 | 0 | 1 | 3 | 2.90 | .263 | 1.05 | 7.7 | 1.9 | 8.6 | 68.1 | 58 | 23 | 22 | 8 | 14 | 65 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 3.28 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 64 | 0 | 3 | 3 | 4.78 | .328 | 1.44 | 8.5 | 4.7 | 9.7 | 52.2 | 49 | 30 | 28 | 5 | 27 | 56 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 3.71 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 43 | 0 | 2 | 3 | 3.95 | .293 | 1.22 | 7.7 | 3.3 | 7.0 | 41.0 | 35 | 18 | 18 | 9 | 15 | 32 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 5.46 |