| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 15 | 15 | 6 | 7 | 3.83 | .282 | 1.17 | 7.8 | 2.8 | 9.4 | 101.0 | 87 | 43 | 43 | 16 | 31 | 105 | 0 | 0 | 0 | 0 | 9 | 1 | 1 | 3.93 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 15 | 15 | 7 | 4 | 3.60 | .281 | 1.15 | 7.9 | 2.5 | 9.8 | 110.0 | 96 | 46 | 44 | 15 | 30 | 120 | 1 | 0 | 0 | 1 | 8 | 3 | 2 | 3.49 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 15 | 15 | 6 | 4 | 4.04 | .294 | 1.23 | 7.7 | 3.4 | 9.1 | 91.1 | 78 | 41 | 41 | 18 | 34 | 92 | 0 | 0 | 0 | 0 | 8 | 2 | 4 | 4.74 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 85 | 15 | 15 | 3 | 9 | 5.99 | .348 | 1.59 | 11.1 | 3.3 | 10.1 | 76.2 | 94 | 51 | 51 | 7 | 28 | 85 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 3.11 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 73 | 15 | 15 | 6 | 7 | 5.01 | .338 | 1.50 | 10.4 | 3.2 | 6.1 | 100.2 | 116 | 61 | 56 | 13 | 35 | 68 | 3 | 0 | 0 | 1 | 8 | 3 | 1 | 4.47 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 30 | 0 | 0 | 4 | 1.80 | .308 | 1.33 | 6.0 | 6.0 | 10.5 | 30.0 | 20 | 6 | 6 | 2 | 20 | 35 | 0 | 20 | 1 | 0 | 0 | 0 | 4 | 3.53 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 40 | 0 | 1 | 0 | 2.31 | .235 | 0.90 | 5.3 | 2.9 | 10.0 | 46.2 | 27 | 12 | 12 | 5 | 15 | 51 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.24 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 33 | 0 | 1 | 0 | 2.70 | .302 | 1.30 | 6.3 | 5.4 | 10.8 | 20.0 | 14 | 6 | 6 | 2 | 12 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 3.70 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 60 | 11 | 0 | 0 | 0 | 4.05 | .322 | 1.35 | 7.6 | 4.8 | 8.3 | 13.1 | 11 | 6 | 6 | 3 | 7 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.00 |