| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 34 | 34 | 7 | 18 | 5.15 | .334 | 1.48 | 9.9 | 3.4 | 8.7 | 187.0 | 206 | 111 | 107 | 37 | 70 | 181 | 1 | 0 | 0 | 0 | 16 | 5 | 3 | 4.84 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 88 | 33 | 33 | 12 | 13 | 5.01 | .297 | 1.22 | 8.7 | 2.3 | 6.5 | 163.1 | 158 | 96 | 91 | 36 | 42 | 118 | 0 | 0 | 0 | 0 | 12 | 7 | 2 | 5.33 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 77 | 32 | 32 | 11 | 14 | 5.24 | .340 | 1.53 | 10.8 | 3.0 | 6.0 | 185.2 | 222 | 112 | 108 | 30 | 62 | 124 | 1 | 0 | 0 | 0 | 14 | 3 | 8 | 4.82 |
| SP | Harvey, M.Harvey, Matt # >> | 24 | 2013 | R | 76 | 34 | 32 | 10 | 10 | 5.28 | .321 | 1.37 | 9.4 | 3.0 | 9.7 | 180.2 | 188 | 107 | 106 | 31 | 60 | 193 | 2 | 0 | 0 | 0 | 14 | 8 | 0 | 4.23 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 71 | 34 | 31 | 5 | 16 | 6.24 | .347 | 1.58 | 10.0 | 4.3 | 5.9 | 167.1 | 186 | 124 | 116 | 35 | 79 | 109 | 0 | 0 | 0 | 0 | 8 | 2 | 8 | 5.87 |
| CL | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 82 | 79 | 0 | 4 | 2 | 3.82 | .318 | 1.38 | 7.5 | 5.0 | 8.7 | 96.2 | 80 | 45 | 41 | 15 | 53 | 93 | 0 | 13 | 10 | 0 | 0 | 2 | 0 | 4.81 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 86 | 0 | 2 | 2 | 4.36 | .334 | 1.51 | 7.9 | 5.7 | 11.5 | 97.0 | 85 | 52 | 47 | 16 | 61 | 124 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 4.47 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 95 | 0 | 5 | 4 | 3.81 | .336 | 1.49 | 8.7 | 4.8 | 11.3 | 108.2 | 104 | 49 | 46 | 13 | 58 | 136 | 0 | 3 | 4 | 0 | 0 | 3 | 7 | 3.74 |
| RP | Foulke, K.Foulke, Keith # >> | 31 | 2003 | R | 56 | 63 | 0 | 2 | 4 | 3.79 | .289 | 1.22 | 8.1 | 3.0 | 9.2 | 73.2 | 66 | 33 | 31 | 12 | 24 | 75 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.07 |