| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 7 | 15 | 5.80 | .338 | 1.51 | 10.3 | 3.3 | 8.9 | 198.2 | 227 | 135 | 128 | 29 | 72 | 195 | 1 | 0 | 0 | 0 | 13 | 5 | 4 | 4.10 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 32 | 32 | 10 | 13 | 6.13 | .354 | 1.63 | 10.4 | 4.3 | 5.0 | 195.1 | 225 | 143 | 133 | 37 | 94 | 108 | 3 | 0 | 0 | 1 | 10 | 2 | 1 | 5.84 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 32 | 32 | 11 | 20 | 6.02 | .345 | 1.56 | 10.3 | 3.7 | 5.4 | 197.1 | 225 | 138 | 132 | 41 | 82 | 118 | 10 | 0 | 0 | 2 | 8 | 5 | 6 | 5.83 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 78 | 32 | 32 | 17 | 11 | 3.40 | .279 | 1.14 | 7.0 | 3.3 | 5.9 | 233.0 | 180 | 93 | 88 | 22 | 86 | 153 | 9 | 0 | 0 | 2 | 23 | 4 | 5 | 4.07 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 31 | 31 | 5 | 18 | 7.02 | .371 | 1.75 | 11.8 | 4.0 | 4.1 | 186.0 | 244 | 151 | 145 | 27 | 82 | 85 | 1 | 0 | 0 | 0 | 8 | 3 | 6 | 5.34 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 64 | 0 | 1 | 5 | 4.45 | .317 | 1.35 | 7.2 | 5.0 | 9.8 | 89.0 | 71 | 50 | 44 | 11 | 49 | 97 | 0 | 1 | 3 | 0 | 0 | 4 | 3 | 4.21 |
| RP | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 94 | 62 | 0 | 10 | 1 | 3.04 | .295 | 1.24 | 6.1 | 5.1 | 11.2 | 71.0 | 48 | 26 | 24 | 6 | 40 | 88 | 0 | 4 | 1 | 0 | 0 | 1 | 3 | 3.35 |
| RP | Papelbon, J.Papelbon, Jonathan # >> | 27 | 2007 | R | 92 | 48 | 0 | 2 | 1 | 4.47 | .343 | 1.57 | 9.2 | 5.0 | 7.8 | 52.1 | 53 | 28 | 26 | 9 | 29 | 45 | 0 | 5 | 3 | 0 | 0 | 0 | 0 | 5.19 |