| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 22 | 22 | 12 | 6 | 2.12 | .251 | 0.99 | 5.9 | 2.9 | 4.8 | 153.0 | 101 | 42 | 36 | 7 | 50 | 82 | 3 | 0 | 0 | 1 | 18 | 3 | 2 | 3.56 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 21 | 21 | 3 | 9 | 4.19 | .284 | 1.16 | 7.0 | 3.5 | 7.8 | 116.0 | 90 | 55 | 54 | 14 | 45 | 101 | 0 | 0 | 0 | 0 | 9 | 3 | 1 | 4.07 |
| SP | Lundgren, C.Lundgren, Carl † >> | 27 | 1907 | R | 42 | 21 | 21 | 12 | 4 | 2.15 | .261 | 1.03 | 6.0 | 3.3 | 3.3 | 155.0 | 103 | 45 | 37 | 7 | 56 | 56 | 3 | 0 | 0 | 2 | 18 | 5 | 1 | 4.05 |
| SP | Fernandez, S.Fernandez, Sid # >> | 23 | 1985 | L | 49 | 21 | 21 | 9 | 5 | 3.09 | .271 | 1.09 | 6.3 | 3.6 | 8.6 | 128.0 | 89 | 49 | 44 | 11 | 51 | 123 | 4 | 0 | 0 | 1 | 13 | 3 | 1 | 3.46 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 20 | 20 | 9 | 2 | 4.33 | .307 | 1.32 | 8.1 | 3.7 | 7.4 | 104.0 | 94 | 50 | 50 | 14 | 43 | 86 | 0 | 0 | 0 | 0 | 8 | 1 | 0 | 4.37 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 63 | 0 | 3 | 1 | 3.14 | .276 | 1.12 | 6.5 | 3.7 | 7.8 | 51.2 | 37 | 19 | 18 | 2 | 21 | 44 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 3.08 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 48 | 0 | 2 | 0 | 3.89 | .273 | 1.13 | 6.1 | 4.2 | 9.3 | 34.2 | 23 | 15 | 15 | 3 | 16 | 35 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 3.50 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 31 | 29 | 0 | 1 | 2 | 2.82 | .280 | 1.16 | 6.5 | 4.1 | 7.8 | 22.1 | 16 | 8 | 7 | 1 | 10 | 19 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 3.23 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 33 | 0 | 3 | 0 | 4.62 | .283 | 1.18 | 6.1 | 4.7 | 10.8 | 25.1 | 17 | 13 | 13 | 1 | 13 | 30 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 2.68 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 29 | 0 | 3 | 0 | 1.38 | .225 | 0.87 | 4.8 | 3.0 | 4.2 | 39.0 | 21 | 6 | 6 | 1 | 13 | 18 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 3.41 |