| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 23 | 23 | 6 | 16 | 3.76 | .308 | 1.32 | 9.7 | 2.2 | 8.6 | 177.0 | 191 | 87 | 74 | 19 | 43 | 170 | 8 | 0 | 0 | 1 | 13 | 2 | 4 | 3.24 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 22 | 22 | 7 | 5 | 5.54 | .323 | 1.41 | 9.9 | 2.8 | 8.0 | 133.1 | 146 | 90 | 82 | 20 | 42 | 118 | 0 | 0 | 0 | 0 | 8 | 3 | 8 | 4.20 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 22 | 22 | 7 | 12 | 5.40 | .351 | 1.59 | 10.8 | 3.6 | 4.8 | 158.1 | 189 | 124 | 95 | 20 | 63 | 84 | 4 | 0 | 0 | 1 | 8 | 5 | 3 | 4.87 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 20 | 20 | 8 | 10 | 5.06 | .354 | 1.58 | 10.1 | 4.1 | 5.0 | 137.0 | 154 | 93 | 77 | 20 | 62 | 76 | 6 | 0 | 0 | 1 | 8 | 9 | 10 | 5.34 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 49 | 0 | 2 | 3 | 3.29 | .256 | 0.98 | 7.1 | 1.7 | 9.1 | 63.0 | 50 | 24 | 23 | 9 | 12 | 64 | 0 | 4 | 3 | 0 | 0 | 3 | 0 | 3.54 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 50 | 0 | 2 | 2 | 4.24 | .298 | 1.27 | 7.8 | 3.7 | 8.5 | 51.0 | 44 | 27 | 24 | 9 | 21 | 48 | 0 | 7 | 2 | 0 | 0 | 0 | 3 | 4.65 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 29 | 0 | 0 | 2 | 1.65 | .322 | 1.35 | 7.3 | 5.0 | 10.0 | 27.1 | 22 | 8 | 5 | 0 | 15 | 30 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 2.67 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 17 | 0 | 0 | 1 | 5.85 | .375 | 1.80 | 12.6 | 3.6 | 6.3 | 20.0 | 28 | 15 | 13 | 5 | 8 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 6.05 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 7 | 0 | 1 | 1 | 5.14 | .323 | 1.43 | 10.3 | 2.6 | 7.7 | 7.0 | 8 | 4 | 4 | 2 | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.86 |