| SP | Harden, R.Harden, Rich $ >> | 27 | 2008 | R | 95 | 25 | 25 | 12 | 6 | 4.17 | .321 | 1.38 | 8.7 | 3.7 | 8.9 | 138.0 | 134 | 70 | 64 | 18 | 57 | 137 | 0 | 0 | 0 | 0 | 11 | 5 | 2 | 4.06 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 23 | 23 | 10 | 7 | 4.50 | .305 | 1.32 | 8.7 | 3.1 | 7.0 | 126.0 | 122 | 63 | 63 | 20 | 44 | 98 | 0 | 0 | 0 | 0 | 10 | 0 | 1 | 4.56 |
| SP | Webb, B.Webb, Brandon # >> | 24 | 2003 | R | 64 | 23 | 23 | 7 | 6 | 4.28 | .293 | 1.23 | 7.9 | 3.2 | 8.0 | 120.0 | 105 | 60 | 57 | 23 | 42 | 106 | 0 | 0 | 0 | 0 | 8 | 2 | 4 | 4.83 |
| RP | Wagner, B.Wagner, Billy >> | 34 | 2005 | L | 92 | 78 | 0 | 4 | 1 | 2.48 | .272 | 1.10 | 6.1 | 3.9 | 9.8 | 58.0 | 39 | 17 | 16 | 7 | 25 | 63 | 0 | 3 | 2 | 0 | 0 | 1 | 2 | 3.74 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 79 | 72 | 0 | 3 | 2 | 4.10 | .265 | 1.02 | 6.7 | 2.6 | 8.3 | 63.2 | 47 | 29 | 29 | 8 | 18 | 58 | 0 | 10 | 2 | 0 | 0 | 4 | 0 | 3.86 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 70 | 45 | 0 | 1 | 0 | 1.91 | .240 | 0.92 | 4.7 | 3.6 | 10.7 | 42.1 | 22 | 9 | 9 | 1 | 17 | 50 | 0 | 11 | 2 | 0 | 0 | 1 | 0 | 2.21 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 55 | 55 | 0 | 1 | 3 | 5.26 | .389 | 1.87 | 10.8 | 6.5 | 12.6 | 25.2 | 30 | 16 | 15 | 3 | 18 | 35 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 4.04 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 86 | 29 | 0 | 2 | 2 | 1.91 | .214 | 0.76 | 3.5 | 3.3 | 10.6 | 33.0 | 13 | 9 | 7 | 4 | 12 | 39 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 3.48 |
| RP | Remlinger, M.Remlinger, Mike >> | 36 | 2002 | L | 36 | 35 | 0 | 0 | 2 | 2.94 | .273 | 1.10 | 6.8 | 3.3 | 10.4 | 33.2 | 25 | 11 | 11 | 5 | 12 | 38 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 3.85 |