| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 28 | 28 | 12 | 12 | 3.81 | .297 | 1.27 | 8.6 | 2.8 | 8.7 | 196.0 | 187 | 87 | 83 | 18 | 61 | 190 | 3 | 0 | 0 | 2 | 15 | 1 | 0 | 3.20 |
| SP | McNally, D.McNally, Dave # >> | 26 | 1968 | L | 96 | 27 | 27 | 9 | 12 | 4.00 | .298 | 1.24 | 8.6 | 2.6 | 5.4 | 202.2 | 194 | 92 | 90 | 24 | 58 | 121 | 10 | 0 | 0 | 1 | 15 | 6 | 1 | 4.30 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 27 | 27 | 12 | 5 | 5.21 | .313 | 1.37 | 9.1 | 3.3 | 8.9 | 174.1 | 175 | 102 | 101 | 29 | 63 | 173 | 1 | 0 | 0 | 1 | 13 | 0 | 6 | 4.26 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 27 | 27 | 11 | 7 | 4.09 | .296 | 1.24 | 8.5 | 2.7 | 4.8 | 141.0 | 133 | 66 | 64 | 13 | 42 | 75 | 0 | 0 | 0 | 0 | 10 | 3 | 1 | 4.09 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 26 | 26 | 10 | 12 | 6.91 | .365 | 1.71 | 11.2 | 4.2 | 7.2 | 125.0 | 156 | 99 | 96 | 19 | 58 | 100 | 0 | 0 | 0 | 0 | 10 | 2 | 6 | 4.82 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 62 | 0 | 2 | 3 | 3.24 | .292 | 1.20 | 8.0 | 2.8 | 8.7 | 83.1 | 74 | 37 | 30 | 8 | 26 | 80 | 0 | 9 | 1 | 0 | 0 | 3 | 0 | 3.37 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 32 | 0 | 4 | 2 | 6.63 | .333 | 1.50 | 10.2 | 3.3 | 6.9 | 38.0 | 43 | 29 | 28 | 7 | 14 | 29 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.97 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 34 | 0 | 0 | 2 | 4.32 | .302 | 1.30 | 9.2 | 2.6 | 8.3 | 41.2 | 42 | 21 | 20 | 5 | 12 | 38 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 3.61 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 7 | 0 | 0 | 1 | 3.38 | .304 | 1.31 | 10.8 | 1.8 | 4.5 | 10.2 | 12 | 7 | 4 | 0 | 2 | 5 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.60 |