| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 25 | 25 | 10 | 7 | 3.10 | .265 | 1.07 | 7.7 | 1.9 | 5.6 | 177.1 | 152 | 68 | 61 | 15 | 37 | 111 | 5 | 0 | 0 | 0 | 17 | 3 | 3 | 3.53 |
| SP | Brown, M.Brown, Mordecai † >> | 32 | 1908 | R | 85 | 24 | 24 | 11 | 7 | 2.93 | .276 | 1.13 | 7.4 | 2.8 | 4.9 | 184.0 | 151 | 66 | 60 | 18 | 57 | 100 | 5 | 0 | 0 | 1 | 16 | 2 | 5 | 4.15 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 22 | 22 | 7 | 7 | 4.09 | .320 | 1.36 | 7.9 | 4.4 | 3.6 | 140.2 | 123 | 68 | 64 | 7 | 69 | 56 | 3 | 0 | 0 | 0 | 14 | 7 | 2 | 4.48 |
| RP | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 86 | 59 | 0 | 6 | 4 | 3.13 | .275 | 1.11 | 7.1 | 2.9 | 7.5 | 72.0 | 57 | 27 | 25 | 10 | 23 | 60 | 0 | 12 | 6 | 0 | 0 | 2 | 1 | 4.18 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 36 | 0 | 3 | 3 | 2.68 | .284 | 1.14 | 7.5 | 2.7 | 10.2 | 37.0 | 31 | 11 | 11 | 3 | 11 | 42 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 2.84 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 23 | 0 | 2 | 2 | 2.28 | .304 | 1.27 | 7.0 | 4.7 | 9.4 | 23.2 | 18 | 6 | 6 | 1 | 12 | 24 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.17 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 12 | 0 | 2 | 0 | 2.81 | .250 | 1.00 | 6.2 | 2.8 | 5.6 | 16.0 | 11 | 5 | 5 | 0 | 5 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.69 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 11 | 0 | 2 | 2 | 3.00 | .270 | 1.11 | 7.0 | 3.0 | 6.0 | 9.0 | 7 | 3 | 3 | 1 | 3 | 6 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.11 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 6 | 0 | 0 | 0 | 0.00 | .103 | 0.35 | 3.4 | 0.0 | 7.9 | 8.2 | 3 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.25 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 54 | 14 | 0 | 0 | 2 | 4.85 | .339 | 1.54 | 9.7 | 4.2 | 5.5 | 13.0 | 14 | 7 | 7 | 3 | 6 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.15 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 16 | 0 | 2 | 0 | 4.70 | .305 | 1.29 | 9.5 | 2.3 | 4.4 | 76.2 | 80 | 40 | 40 | 4 | 19 | 37 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 3.54 |