| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 28 | 28 | 11 | 9 | 4.08 | .308 | 1.34 | 8.7 | 3.3 | 8.7 | 176.2 | 171 | 88 | 80 | 19 | 65 | 170 | 2 | 0 | 0 | 1 | 17 | 0 | 3 | 3.58 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 28 | 28 | 7 | 12 | 5.92 | .334 | 1.50 | 10.4 | 3.2 | 7.3 | 170.1 | 196 | 115 | 112 | 27 | 60 | 138 | 4 | 0 | 0 | 0 | 11 | 0 | 5 | 4.50 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 25 | 25 | 9 | 13 | 5.02 | .337 | 1.52 | 9.8 | 3.9 | 5.1 | 174.0 | 189 | 104 | 97 | 21 | 75 | 98 | 6 | 0 | 0 | 3 | 10 | 1 | 3 | 4.75 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 27 | 27 | 6 | 14 | 5.31 | .354 | 1.61 | 10.0 | 4.6 | 5.7 | 162.2 | 180 | 101 | 96 | 20 | 82 | 102 | 3 | 0 | 0 | 1 | 11 | 5 | 6 | 4.96 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 76 | 0 | 9 | 2 | 2.32 | .232 | 0.88 | 5.3 | 2.7 | 10.4 | 100.2 | 59 | 28 | 26 | 4 | 30 | 115 | 0 | 5 | 2 | 0 | 0 | 2 | 6 | 2.18 |
| RP | Uehara, K.Uehara, Koji # >> | 38 | 2013 | R | 100 | 59 | 0 | 3 | 3 | 4.81 | .306 | 1.31 | 8.5 | 3.4 | 8.6 | 67.1 | 63 | 37 | 36 | 8 | 25 | 64 | 0 | 5 | 2 | 0 | 0 | 1 | 0 | 3.81 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 39 | 0 | 5 | 4 | 3.74 | .293 | 1.23 | 6.8 | 4.2 | 6.5 | 53.0 | 40 | 22 | 22 | 8 | 25 | 38 | 0 | 4 | 1 | 0 | 0 | 1 | 4 | 5.00 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 38 | 0 | 3 | 4 | 3.51 | .317 | 1.39 | 8.8 | 3.7 | 6.8 | 41.0 | 40 | 17 | 16 | 4 | 17 | 31 | 0 | 7 | 2 | 0 | 0 | 0 | 0 | 4.00 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 5 | 2 | 1 | 2 | 3.86 | .288 | 1.21 | 5.8 | 5.1 | 9.6 | 14.0 | 9 | 6 | 6 | 1 | 8 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.50 |