| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 24 | 24 | 11 | 8 | 3.35 | .281 | 1.16 | 7.3 | 3.1 | 8.8 | 193.1 | 157 | 75 | 72 | 16 | 67 | 189 | 9 | 0 | 0 | 2 | 14 | 3 | 4 | 3.21 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 24 | 24 | 8 | 9 | 4.50 | .331 | 1.46 | 9.4 | 3.7 | 5.6 | 162.0 | 170 | 84 | 81 | 14 | 66 | 101 | 3 | 0 | 0 | 0 | 12 | 4 | 3 | 4.17 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 22 | 22 | 7 | 12 | 5.08 | .333 | 1.46 | 9.9 | 3.3 | 5.1 | 125.2 | 137 | 79 | 71 | 14 | 46 | 71 | 0 | 0 | 0 | 0 | 10 | 5 | 1 | 4.54 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 98 | 65 | 0 | 6 | 4 | 3.65 | .279 | 1.12 | 7.8 | 2.3 | 8.7 | 86.1 | 75 | 37 | 35 | 8 | 22 | 83 | 0 | 7 | 3 | 0 | 0 | 3 | 0 | 3.15 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 52 | 0 | 0 | 3 | 4.04 | .307 | 1.31 | 8.6 | 3.4 | 7.9 | 64.2 | 61 | 33 | 29 | 10 | 24 | 56 | 0 | 8 | 3 | 0 | 0 | 1 | 0 | 4.45 |
| RP | Davis, W.Davis, Wade # >> | 29 | 2015 | R | 89 | 33 | 0 | 4 | 3 | 5.31 | .341 | 1.55 | 9.2 | 5.0 | 10.1 | 40.2 | 41 | 24 | 24 | 7 | 22 | 45 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 4.68 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 30 | 0 | 2 | 4 | 3.38 | .284 | 1.13 | 7.9 | 2.3 | 9.0 | 32.0 | 28 | 14 | 12 | 0 | 8 | 32 | 0 | 5 | 1 | 0 | 0 | 2 | 0 | 1.94 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 17 | 0 | 2 | 0 | 3.48 | .295 | 1.26 | 6.8 | 5.0 | 8.1 | 20.2 | 15 | 8 | 8 | 2 | 11 | 18 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 4.15 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 22 | 0 | 1 | 1 | 1.65 | .216 | 0.80 | 5.6 | 1.7 | 4.2 | 32.2 | 20 | 7 | 6 | 2 | 6 | 15 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 3.53 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 1 | 0 | 0 | 0 | 54.00 | .667 | 6.00 | - | - | - | 0.1 | 2 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |