| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 24 | 24 | 6 | 10 | 4.42 | .298 | 1.25 | 8.5 | 2.7 | 8.1 | 165.0 | 156 | 86 | 81 | 31 | 50 | 149 | 0 | 0 | 0 | 0 | 14 | 4 | 1 | 4.62 |
| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 93 | 24 | 24 | 7 | 12 | 5.33 | .320 | 1.39 | 9.3 | 3.2 | 7.0 | 165.1 | 171 | 101 | 98 | 20 | 58 | 129 | 4 | 0 | 0 | 1 | 9 | 4 | 5 | 4.14 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 24 | 24 | 8 | 9 | 4.37 | .316 | 1.36 | 9.0 | 3.2 | 9.0 | 173.0 | 173 | 91 | 84 | 24 | 62 | 173 | 3 | 0 | 0 | 1 | 11 | 5 | 1 | 3.97 |
| RP | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 61 | 0 | 8 | 4 | 4.28 | .300 | 1.26 | 8.6 | 2.8 | 8.8 | 80.0 | 76 | 43 | 38 | 9 | 25 | 78 | 0 | 5 | 6 | 0 | 0 | 2 | 0 | 3.53 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 45 | 0 | 1 | 1 | 4.18 | .307 | 1.31 | 8.8 | 3.1 | 9.2 | 47.1 | 46 | 27 | 22 | 7 | 16 | 48 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 3.98 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 24 | 0 | 2 | 0 | 4.32 | .353 | 1.56 | 9.7 | 4.3 | 8.6 | 25.0 | 27 | 16 | 12 | 4 | 12 | 24 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.84 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 17 | 0 | 3 | 1 | 4.84 | .280 | 1.12 | 5.7 | 4.5 | 9.0 | 22.1 | 14 | 12 | 12 | 1 | 11 | 22 | 0 | 2 | 0 | 0 | 0 | 1 | 3 | 3.23 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 4 | 3 | 0 | 3 | 5.75 | .344 | 1.57 | 12.6 | 1.8 | 2.3 | 20.1 | 28 | 13 | 13 | 4 | 4 | 5 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 5.70 |