| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 12 | 12 | 4 | 5 | 3.39 | .320 | 1.41 | 8.9 | 3.8 | 5.4 | 85.0 | 84 | 35 | 32 | 6 | 36 | 51 | 1 | 0 | 0 | 0 | 8 | 0 | 3 | 3.99 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 12 | 12 | 3 | 3 | 4.88 | .333 | 1.49 | 8.5 | 4.9 | 8.8 | 72.0 | 68 | 44 | 39 | 7 | 39 | 70 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 3.99 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 11 | 11 | 5 | 5 | 4.39 | .275 | 1.13 | 8.1 | 2.0 | 4.8 | 80.0 | 72 | 41 | 39 | 10 | 18 | 43 | 5 | 0 | 0 | 2 | 4 | 1 | 1 | 4.26 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 12 | 11 | 5 | 4 | 3.35 | .271 | 1.09 | 7.4 | 2.5 | 5.6 | 83.1 | 68 | 33 | 31 | 10 | 23 | 52 | 3 | 0 | 0 | 0 | 6 | 2 | 1 | 4.22 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 29 | 0 | 0 | 3 | 5.23 | .315 | 1.32 | 7.9 | 4.2 | 7.9 | 32.2 | 28 | 22 | 19 | 4 | 15 | 28 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 4.47 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 25 | 0 | 1 | 1 | 4.83 | .301 | 1.26 | 7.3 | 4.4 | 7.8 | 31.2 | 25 | 17 | 17 | 2 | 15 | 27 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.65 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 15 | 0 | 2 | 0 | 6.06 | .279 | 1.16 | 5.1 | 5.6 | 10.1 | 16.1 | 9 | 11 | 11 | 5 | 10 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.69 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 12 | 0 | 1 | 0 | 4.61 | .281 | 1.10 | 7.6 | 2.8 | 11.8 | 13.2 | 11 | 7 | 7 | 1 | 4 | 17 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.54 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 6 | 0 | 0 | 1 | 5.19 | .257 | 1.04 | 9.0 | 1.1 | 6.8 | 8.2 | 8 | 5 | 5 | 1 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.50 |