| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 10 | 10 | 1 | 6 | 5.13 | .301 | 1.26 | 8.4 | 3.1 | 11.3 | 59.2 | 55 | 34 | 34 | 16 | 20 | 74 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 5.14 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 9 | 9 | 5 | 4 | 2.60 | .273 | 1.13 | 8.2 | 2.1 | 6.0 | 65.2 | 59 | 21 | 19 | 9 | 15 | 43 | 1 | 0 | 0 | 0 | 6 | 0 | 0 | 4.17 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 89 | 9 | 9 | 5 | 3 | 4.50 | .294 | 1.23 | 7.8 | 3.3 | 7.8 | 60.0 | 52 | 31 | 30 | 9 | 22 | 52 | 1 | 0 | 0 | 1 | 4 | 1 | 0 | 4.37 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 9 | 9 | 1 | 6 | 7.95 | .365 | 1.71 | 12.0 | 3.6 | 6.4 | 48.2 | 64 | 44 | 43 | 11 | 19 | 34 | 1 | 0 | 0 | 0 | 3 | 1 | 3 | 5.81 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 27 | 0 | 1 | 1 | 3.45 | .265 | 0.98 | 5.1 | 3.9 | 7.7 | 28.2 | 16 | 11 | 11 | 4 | 12 | 24 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 4.75 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 21 | 0 | 0 | 0 | 1.61 | .212 | 0.81 | 5.3 | 2.0 | 7.8 | 22.1 | 13 | 4 | 4 | 1 | 5 | 19 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 2.55 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 11 | 0 | 1 | 2 | 9.00 | .371 | 1.69 | 9.0 | 6.2 | 6.2 | 13.0 | 13 | 15 | 13 | 3 | 9 | 9 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.92 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 12 | 0 | 0 | 1 | 6.75 | .319 | 1.41 | 10.8 | 2.7 | 6.3 | 10.2 | 12 | 8 | 8 | 3 | 3 | 7 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 6.40 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 7 | 0 | 0 | 0 | 8.10 | .412 | 2.10 | 18.0 | 3.0 | 4.5 | 6.2 | 12 | 7 | 6 | 2 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.33 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 4 | 0 | 0 | 0 | 0.00 | .148 | 0.52 | 2.6 | 2.6 | 2.6 | 7.2 | 2 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.29 |